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Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling.

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Title: Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling.
Authors: Santos-Zas I; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Lemarié J; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Zlatanova I; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Cachanado M; Assistance Publique-Hôpitaux de Paris, APHP.SU; Department of Clinical Pharmacology and Clinical Research Platform (URCEST-CRB-CRC-EST), Hôpital Saint Antoine, Paris, France., Seghezzi JC; Service de cardiologie, Centre Hospitalier de Compiegne, Compiegne, France., Benamer H; Service de cardiologie, Institut Cardiovasculaire Paris Sud, Paris, France., Goube P; Service de cardiologie, Centre Hospitalier de Corbeil, Corbeil, France., Vandestienne M; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Cohen R; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Ezzo M; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Duval V; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Zhang Y; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Su JB; Inserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France., Bizé A; Inserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France., Sambin L; Inserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France., Bonnin P; Inserm U965, Department of Physiology, Assistance Publique Hôpitaux de Paris, Hôpital Lariboisière, France., Branchereau M; Inserm U1048-Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), université Paul Sabatier, Toulouse, France., Heymes C; Inserm U1048-Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), université Paul Sabatier, Toulouse, France., Tanchot C; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Vilar J; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Delacroix C; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Hulot JS; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Cochain C; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany., Bruneval P; Université de Paris, PARCC, INSERM, F-75015, Paris, France.; Service d'anatomopathologie, Hôpital Europeen G. Pompidou, Assistance Publique, Hôpitaux de Paris, Paris, France., Danchin N; Service de cardiologie, Hôpital Europeen G. Pompidou, Assistance Publique, Hôpitaux de Paris, Paris, France., Tedgui A; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Mallat Z; Université de Paris, PARCC, INSERM, F-75015, Paris, France.; Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK., Simon T; Assistance Publique-Hôpitaux de Paris, APHP.SU; Department of Clinical Pharmacology and Clinical Research Platform (URCEST-CRB-CRC-EST), Hôpital Saint Antoine, Paris, France.; Sorbonne Université, UPMC-site St Antoine, Service de Pharmacologie, Assistance Publique-Hôpitaux de Paris, APHP.SU; Department of Clinical Pharmacology and Clinical Research Platform (URCEST-CRB-CRC-EST), Hôpital Saint Antoine, Paris, France., Ghaleh B; Inserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France., Silvestre JS; Université de Paris, PARCC, INSERM, F-75015, Paris, France., Ait-Oufella H; Université de Paris, PARCC, INSERM, F-75015, Paris, France. hafid.aitoufella@inserm.fr.; Sorbonne Université, Service de médecine intensive-Réanimation, Assistance Publique, Hôpitaux de Paris, Paris, France. hafid.aitoufella@inserm.fr.
Source: Nature communications [Nat Commun] 2021 Mar 05; Vol. 12 (1), pp. 1483. Date of Electronic Publication: 2021 Mar 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cytotoxic CD8<superscript>+</superscript> T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling.
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  Data: <searchLink fieldCode="AU" term="%22Santos-Zas+I%22">Santos-Zas I</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lemarié+J%22">Lemarié J</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Zlatanova+I%22">Zlatanova I</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cachanado+M%22">Cachanado M</searchLink>; Assistance Publique-Hôpitaux de Paris, APHP.SU; Department of Clinical Pharmacology and Clinical Research Platform (URCEST-CRB-CRC-EST), Hôpital Saint Antoine, Paris, France.<br /><searchLink fieldCode="AU" term="%22Seghezzi+JC%22">Seghezzi JC</searchLink>; Service de cardiologie, Centre Hospitalier de Compiegne, Compiegne, France.<br /><searchLink fieldCode="AU" term="%22Benamer+H%22">Benamer H</searchLink>; Service de cardiologie, Institut Cardiovasculaire Paris Sud, Paris, France.<br /><searchLink fieldCode="AU" term="%22Goube+P%22">Goube P</searchLink>; Service de cardiologie, Centre Hospitalier de Corbeil, Corbeil, France.<br /><searchLink fieldCode="AU" term="%22Vandestienne+M%22">Vandestienne M</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cohen+R%22">Cohen R</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ezzo+M%22">Ezzo M</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Duval+V%22">Duval V</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Su+JB%22">Su JB</searchLink>; Inserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.<br /><searchLink fieldCode="AU" term="%22Bizé+A%22">Bizé A</searchLink>; Inserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.<br /><searchLink fieldCode="AU" term="%22Sambin+L%22">Sambin L</searchLink>; Inserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.<br /><searchLink fieldCode="AU" term="%22Bonnin+P%22">Bonnin P</searchLink>; Inserm U965, Department of Physiology, Assistance Publique Hôpitaux de Paris, Hôpital Lariboisière, France.<br /><searchLink fieldCode="AU" term="%22Branchereau+M%22">Branchereau M</searchLink>; Inserm U1048-Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), université Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Heymes+C%22">Heymes C</searchLink>; Inserm U1048-Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), université Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Tanchot+C%22">Tanchot C</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Vilar+J%22">Vilar J</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Delacroix+C%22">Delacroix C</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hulot+JS%22">Hulot JS</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cochain+C%22">Cochain C</searchLink>; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bruneval+P%22">Bruneval P</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.; Service d'anatomopathologie, Hôpital Europeen G. Pompidou, Assistance Publique, Hôpitaux de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Danchin+N%22">Danchin N</searchLink>; Service de cardiologie, Hôpital Europeen G. Pompidou, Assistance Publique, Hôpitaux de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Tedgui+A%22">Tedgui A</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mallat+Z%22">Mallat Z</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.; Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK.<br /><searchLink fieldCode="AU" term="%22Simon+T%22">Simon T</searchLink>; Assistance Publique-Hôpitaux de Paris, APHP.SU; Department of Clinical Pharmacology and Clinical Research Platform (URCEST-CRB-CRC-EST), Hôpital Saint Antoine, Paris, France.; Sorbonne Université, UPMC-site St Antoine, Service de Pharmacologie, Assistance Publique-Hôpitaux de Paris, APHP.SU; Department of Clinical Pharmacology and Clinical Research Platform (URCEST-CRB-CRC-EST), Hôpital Saint Antoine, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ghaleh+B%22">Ghaleh B</searchLink>; Inserm U955-IMRB, Equipe 03, UPEC, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.<br /><searchLink fieldCode="AU" term="%22Silvestre+JS%22">Silvestre JS</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ait-Oufella+H%22">Ait-Oufella H</searchLink>; Université de Paris, PARCC, INSERM, F-75015, Paris, France. hafid.aitoufella@inserm.fr.; Sorbonne Université, Service de médecine intensive-Réanimation, Assistance Publique, Hôpitaux de Paris, Paris, France. hafid.aitoufella@inserm.fr.
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