Protective Effects of Novel Substituted Triazinoindole Inhibitors of Aldose Reductase and Epalrestat in Neuron-like PC12 Cells and BV2 Rodent Microglial Cells Exposed to Toxic Models of Oxidative Stress: Comparison with the Pyridoindole Antioxidant Stobadine.
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| Title: | Protective Effects of Novel Substituted Triazinoindole Inhibitors of Aldose Reductase and Epalrestat in Neuron-like PC12 Cells and BV2 Rodent Microglial Cells Exposed to Toxic Models of Oxidative Stress: Comparison with the Pyridoindole Antioxidant Stobadine. |
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| Authors: | Elmazoglu Z; Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Department of Medical Pharmacology, Gazi University, Beşevler, 06500, Ankara, Turkey., Prnova MS; Institute of Experimental Pharmacology and Toxicology, CEM, Slovak Academy of Sciences, Dubravska cesta 9, 84104, Bratislava, Slovakia., Stefek M; Institute of Experimental Pharmacology and Toxicology, CEM, Slovak Academy of Sciences, Dubravska cesta 9, 84104, Bratislava, Slovakia., Ceylan AF; Department of Medical Pharmacology, Faculty of Medicine, Ankara Yildirim Beyazit University Bilkent, 06800, Ankara, Turkey., Aschner M; Albert Einstein College of Medicine, Jack and Pearl Resnick Campus, Bronx, NY, 10461, USA., Rangel-López E; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología Y Neurocirugía, S.S.A, 14269, Mexico City, Mexico., Santamaria A; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología Y Neurocirugía, S.S.A, 14269, Mexico City, Mexico. absada@yahoo.com., Karasu C; Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Department of Medical Pharmacology, Gazi University, Beşevler, 06500, Ankara, Turkey. cimenkrs@gmail.com. |
| Source: | Neurotoxicity research [Neurotox Res] 2021 Jun; Vol. 39 (3), pp. 588-597. Date of Electronic Publication: 2021 Mar 13. |
| Publication Type: | Comparative Study; Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-3524 (Electronic) Linking ISSN: 10298428 NLM ISO Abbreviation: Neurotox Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1476-3524 |
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| DOI: | 10.1007/s12640-021-00349-7 |