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Interpreting Sequence Variation in PDAC-Predisposing Genes Using a Multi-Tier Annotation Approach Performed at the Gene, Patient, and Cohort Level.

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Title: Interpreting Sequence Variation in PDAC-Predisposing Genes Using a Multi-Tier Annotation Approach Performed at the Gene, Patient, and Cohort Level.
Authors: Zimmermann MT; Bioinformatics Research and Development Laboratory, Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, United States.; Clinical and Translational Sciences Institute, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States., Mathison AJ; Division of Research, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.; Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, United States., Stodola T; Division of Research, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States., Evans DB; Division of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.; LaBahn Pancreatic Cancer Program, Medical College of Wisconsin, Milwaukee, WI, United States., Abrudan JL; Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, United States., Demos W; Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, United States., Tschannen M; Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, United States., Aldakkak M; Division of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States., Geurts J; Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, United States.; Genetic Counseling Program, Medical College of Wisconsin, Milwaukee, WI, United States., Lomberk G; Division of Research, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.; Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, United States.; LaBahn Pancreatic Cancer Program, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI, United States., Tsai S; Division of Research, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.; Division of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.; LaBahn Pancreatic Cancer Program, Medical College of Wisconsin, Milwaukee, WI, United States., Urrutia R; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, United States.; Division of Research, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.; Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, United States.; LaBahn Pancreatic Cancer Program, Medical College of Wisconsin, Milwaukee, WI, United States.
Source: Frontiers in oncology [Front Oncol] 2021 Mar 05; Vol. 11, pp. 606820. Date of Electronic Publication: 2021 Mar 05 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
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