Pacritinib Combined with Sirolimus and Low-Dose Tacrolimus for GVHD Prevention after Allogeneic Hematopoietic Cell Transplantation: Preclinical and Phase I Trial Results.
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| Title: | Pacritinib Combined with Sirolimus and Low-Dose Tacrolimus for GVHD Prevention after Allogeneic Hematopoietic Cell Transplantation: Preclinical and Phase I Trial Results. |
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| Authors: | Pidala J; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Immunology, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Walton K; Division of Hematology, Oncology, and Transplantation, Department of Medicine, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Elmariah H; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Kim J; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida., Mishra A; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Bejanyan N; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Nishihori T; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Khimani F; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Perez L; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Faramand RG; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Davila ML; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Immunology, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Nieder ML; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Sagatys EM; Department of Hematopathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, Florida., Holtan SG; Division of Hematology, Oncology, and Transplantation, Department of Medicine, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Lawrence NJ; Department of Drug Discovery, Moffitt Cancer Center, Tampa, Florida., Lawrence HR; Department of Drug Discovery, Moffitt Cancer Center, Tampa, Florida., Blazar BR; Division of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Anasetti C; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Immunology, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida., Sebti SM; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia., Betts BC; Division of Hematology, Oncology, and Transplantation, Department of Medicine, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota. bett0121@umn.edu. |
| Source: | Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 May 15; Vol. 27 (10), pp. 2712-2722. Date of Electronic Publication: 2021 Mar 22. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 33753457 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Pacritinib Combined with Sirolimus and Low-Dose Tacrolimus for GVHD Prevention after Allogeneic Hematopoietic Cell Transplantation: Preclinical and Phase I Trial Results. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Pidala+J%22">Pidala J</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Immunology, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Walton+K%22">Walton K</searchLink>; Division of Hematology, Oncology, and Transplantation, Department of Medicine, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Elmariah+H%22">Elmariah H</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Mishra+A%22">Mishra A</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Bejanyan+N%22">Bejanyan N</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Nishihori+T%22">Nishihori T</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Khimani+F%22">Khimani F</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Perez+L%22">Perez L</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Faramand+RG%22">Faramand RG</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Davila+ML%22">Davila ML</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Immunology, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Nieder+ML%22">Nieder ML</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Sagatys+EM%22">Sagatys EM</searchLink>; Department of Hematopathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Holtan+SG%22">Holtan SG</searchLink>; Division of Hematology, Oncology, and Transplantation, Department of Medicine, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Lawrence+NJ%22">Lawrence NJ</searchLink>; Department of Drug Discovery, Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Lawrence+HR%22">Lawrence HR</searchLink>; Department of Drug Discovery, Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Blazar+BR%22">Blazar BR</searchLink>; Division of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Anasetti+C%22">Anasetti C</searchLink>; Department of Blood and Marrow Transplantation - Cellular Immunotherapy, Moffitt Cancer Center, Tampa, Florida.; Department of Immunology, Moffitt Cancer Center, Tampa, Florida.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Sebti+SM%22">Sebti SM</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia.<br /><searchLink fieldCode="AU" term="%22Betts+BC%22">Betts BC</searchLink>; Division of Hematology, Oncology, and Transplantation, Department of Medicine, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota. bett0121@umn.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2021 May 15; Vol. 27 (10), pp. 2712-2722. <i>Date of Electronic Publication: </i>2021 Mar 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33753457 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1158/1078-0432.CCR-20-4725 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2712 Titles: – TitleFull: Pacritinib Combined with Sirolimus and Low-Dose Tacrolimus for GVHD Prevention after Allogeneic Hematopoietic Cell Transplantation: Preclinical and Phase I Trial Results. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pidala J – PersonEntity: Name: NameFull: Walton K – PersonEntity: Name: NameFull: Elmariah H – PersonEntity: Name: NameFull: Kim J – PersonEntity: Name: NameFull: Mishra A – PersonEntity: Name: NameFull: Bejanyan N – PersonEntity: Name: NameFull: Nishihori T – PersonEntity: Name: NameFull: Khimani F – PersonEntity: Name: NameFull: Perez L – PersonEntity: Name: NameFull: Faramand RG – PersonEntity: Name: NameFull: Davila ML – PersonEntity: Name: NameFull: Nieder ML – PersonEntity: Name: NameFull: Sagatys EM – PersonEntity: Name: NameFull: Holtan SG – PersonEntity: Name: NameFull: Lawrence NJ – PersonEntity: Name: NameFull: Lawrence HR – PersonEntity: Name: NameFull: Blazar BR – PersonEntity: Name: NameFull: Anasetti C – PersonEntity: Name: NameFull: Sebti SM – PersonEntity: Name: NameFull: Betts BC IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 05 Text: 2021 May 15 Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1557-3265 Numbering: – Type: volume Value: 27 – Type: issue Value: 10 Titles: – TitleFull: Clinical cancer research : an official journal of the American Association for Cancer Research Type: main |
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