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Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation.

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Title: Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation.
Authors: Deng X; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Garcia-Knight MA; Department of Microbiology and Immunology, University of California San Francisco, California, USA., Khalid MM; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., Servellita V; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Wang C; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Morris MK; California Department of Public Health, Richmond, California, USA., Sotomayor-González A; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Glasner DR; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Reyes KR; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Gliwa AS; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Reddy NP; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Martin CSS; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA., Federman S; Laboratory for Genomics Research, University of California San Francisco, California, USA., Cheng J; Department of Medicine, University of California San Francisco, California, USA., Balcerek J; Department of Laboratory Medicine, University of California San Francisco, California, USA., Taylor J; Department of Laboratory Medicine, University of California San Francisco, California, USA., Streithorst JA; Department of Laboratory Medicine, University of California San Francisco, California, USA., Miller S; Department of Laboratory Medicine, University of California San Francisco, California, USA., Kumar GR; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., Sreekumar B; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., Chen PY; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., Schulze-Gahmen U; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., Taha TY; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., Hayashi J; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., Simoneau CR; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., McMahon S; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA., Lidsky PV; Department of Microbiology and Immunology, University of California San Francisco, California, USA., Xiao Y; Department of Microbiology and Immunology, University of California San Francisco, California, USA., Hemarajata P; Los Angeles County Department of Public Health, Los Angeles, California, USA., Green NM; Los Angeles County Department of Public Health, Los Angeles, California, USA., Espinosa A; California Department of Public Health, Richmond, California, USA., Kath C; California Department of Public Health, Richmond, California, USA., Haw M; California Department of Public Health, Richmond, California, USA., Bell J; California Department of Public Health, Richmond, California, USA., Hacker JK; California Department of Public Health, Richmond, California, USA., Hanson C; California Department of Public Health, Richmond, California, USA., Wadford DA; California Department of Public Health, Richmond, California, USA., Anaya C; Monterey County Department of Public Health, Monterey, California, USA., Ferguson D; Monterey County Department of Public Health, Monterey, California, USA., Lareau LF; Department of Bioengineering, University of California Berkeley, Berkeley, California, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, California, USA., Frankino PA; Innovative Genomics Institute, University of California Berkeley, Berkeley, California, USA., Shivram H; Innovative Genomics Institute, University of California Berkeley, Berkeley, California, USA., Wyman SK; Innovative Genomics Institute, University of California Berkeley, Berkeley, California, USA., Ott M; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, California, USA., Andino R; Department of Microbiology and Immunology, University of California San Francisco, California, USA., Chiu CY; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.; Department of Medicine, University of California San Francisco, California, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, California, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Mar 09. Date of Electronic Publication: 2021 Mar 09.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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  Data: Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation.
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  Data: <searchLink fieldCode="AU" term="%22Deng+X%22">Deng X</searchLink>; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Garcia-Knight+MA%22">Garcia-Knight MA</searchLink>; Department of Microbiology and Immunology, University of California San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Khalid+MM%22">Khalid MM</searchLink>; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Servellita+V%22">Servellita V</searchLink>; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Morris+MK%22">Morris MK</searchLink>; California Department of Public Health, Richmond, California, USA.<br /><searchLink fieldCode="AU" term="%22Sotomayor-González+A%22">Sotomayor-González A</searchLink>; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Glasner+DR%22">Glasner DR</searchLink>; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Reyes+KR%22">Reyes KR</searchLink>; Department of Laboratory Medicine, University of California San Francisco, California, USA.; 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Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Chen+PY%22">Chen PY</searchLink>; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Schulze-Gahmen+U%22">Schulze-Gahmen U</searchLink>; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Taha+TY%22">Taha TY</searchLink>; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Hayashi+J%22">Hayashi J</searchLink>; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Simoneau+CR%22">Simoneau CR</searchLink>; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22McMahon+S%22">McMahon S</searchLink>; Department of Medicine, University of California San Francisco, California, USA.; Gladstone Institute of Virology, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Lidsky+PV%22">Lidsky PV</searchLink>; Department of Microbiology and Immunology, University of California San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+Y%22">Xiao Y</searchLink>; Department of Microbiology and Immunology, University of California San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Hemarajata+P%22">Hemarajata P</searchLink>; Los Angeles County Department of Public Health, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Green+NM%22">Green NM</searchLink>; Los Angeles County Department of Public Health, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Espinosa+A%22">Espinosa A</searchLink>; 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Gladstone Institute of Virology, San Francisco, California, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, California, USA.<br /><searchLink fieldCode="AU" term="%22Andino+R%22">Andino R</searchLink>; Department of Microbiology and Immunology, University of California San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Chiu+CY%22">Chiu CY</searchLink>; Department of Laboratory Medicine, University of California San Francisco, California, USA.; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.; Department of Medicine, University of California San Francisco, California, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, California, USA.
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