Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects.

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Title: Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects.
Authors: Gillon JY; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Dennison J; Hammersmith Medicines Research Ltd, London, UK., van den Berg F; Hammersmith Medicines Research Ltd, London, UK.; Invicro, Burlington Danes Building, Imperial College London, Hammersmith Hospital, London, UK., Delhomme S; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Dequatre Cheeseman K; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Peña Rossi C; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Strub Wourgaft N; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Specht S; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Pedrique B; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Monnot F; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Skrabs S; Bayer AG, Wuppertal, Germany., Rodriguez ML; Bayer AG, Wuppertal, Germany., Stass H; Bayer AG, Wuppertal, Germany.
Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2021 Oct; Vol. 87 (10), pp. 3949-3960. Date of Electronic Publication: 2021 Mar 31.
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1365-2125
DOI:10.1111/bcp.14816