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Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects.

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Title: Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects.
Authors: Gillon JY; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Dennison J; Hammersmith Medicines Research Ltd, London, UK., van den Berg F; Hammersmith Medicines Research Ltd, London, UK.; Invicro, Burlington Danes Building, Imperial College London, Hammersmith Hospital, London, UK., Delhomme S; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Dequatre Cheeseman K; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Peña Rossi C; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Strub Wourgaft N; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Specht S; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Pedrique B; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Monnot F; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland., Skrabs S; Bayer AG, Wuppertal, Germany., Rodriguez ML; Bayer AG, Wuppertal, Germany., Stass H; Bayer AG, Wuppertal, Germany.
Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2021 Oct; Vol. 87 (10), pp. 3949-3960. Date of Electronic Publication: 2021 Mar 31.
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects.
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  Data: <searchLink fieldCode="AU" term="%22Gillon+JY%22">Gillon JY</searchLink>; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dennison+J%22">Dennison J</searchLink>; Hammersmith Medicines Research Ltd, London, UK.<br /><searchLink fieldCode="AU" term="%22van+den+Berg+F%22">van den Berg F</searchLink>; Hammersmith Medicines Research Ltd, London, UK.; Invicro, Burlington Danes Building, Imperial College London, Hammersmith Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Delhomme+S%22">Delhomme S</searchLink>; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dequatre+Cheeseman+K%22">Dequatre Cheeseman K</searchLink>; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Peña+Rossi+C%22">Peña Rossi C</searchLink>; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Strub+Wourgaft+N%22">Strub Wourgaft N</searchLink>; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Specht+S%22">Specht S</searchLink>; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pedrique+B%22">Pedrique B</searchLink>; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Monnot+F%22">Monnot F</searchLink>; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Skrabs+S%22">Skrabs S</searchLink>; Bayer AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Rodriguez+ML%22">Rodriguez ML</searchLink>; Bayer AG, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Stass+H%22">Stass H</searchLink>; Bayer AG, Wuppertal, Germany.
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  Data: <searchLink fieldCode="JN" term="%227503323%22">British journal of clinical pharmacology</searchLink> [Br J Clin Pharmacol] 2021 Oct; Vol. 87 (10), pp. 3949-3960. <i>Date of Electronic Publication: </i>2021 Mar 31.
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  Data: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7503323 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2125 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203065251%22">03065251 </searchLink><i>NLM ISO Abbreviation: </i>Br J Clin Pharmacol <i>Subsets: </i>MEDLINE
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