Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas.

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Title: Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas.
Authors: Wu J; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland. jing.wu3@nih.gov., Yuan Y; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Long Priel DA; Neutrophil Monitoring Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland., Fink D; Neutrophil Monitoring Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland., Peer CJ; Clinical Pharmacology Program, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Sissung TM; Clinical Pharmacology Program, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Su YT; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Pang Y; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Yu G; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Butler MK; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Mendoza TR; Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas., Vera E; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Ahmad S; The Clinical Center, NIH, Bethesda, Maryland., Bryla C; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Lindsley M; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Grajkowska E; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Mentges K; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Boris L; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Antony R; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Garren N; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Siegel C; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Lollo N; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Cordova C; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Aboud O; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Theeler BJ; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Burton EM; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Penas-Prado M; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Leeper H; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Gonzales J; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Armstrong TS; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Calvo KR; The Clinical Center, NIH, Bethesda, Maryland., Figg WD; Clinical Pharmacology Program, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Kuhns DB; Neutrophil Monitoring Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland., Gallin JI; The Clinical Center, NIH, Bethesda, Maryland., Gilbert MR; Neuro-Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Jun 15; Vol. 27 (12), pp. 3298-3306. Date of Electronic Publication: 2021 Mar 30.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-20-4730