The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.
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| Title: | The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. |
|---|---|
| Authors: | Jones BE; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA. jones_bryan_edward@lilly.com ester.falconer@abcellera.com., Brown-Augsburger PL; Eli Lilly and Company, Indianapolis, IN 46225, USA., Corbett KS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Westendorf K; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Davies J; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA., Cujec TP; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA., Wiethoff CM; Eli Lilly and Company, Indianapolis, IN 46225, USA., Blackbourne JL; Eli Lilly and Company, Indianapolis, IN 46225, USA., Heinz BA; Eli Lilly and Company, Indianapolis, IN 46225, USA., Foster D; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA., Higgs RE; Eli Lilly and Company, Indianapolis, IN 46225, USA., Balasubramaniam D; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA., Wang L; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Zhang Y; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Yang ES; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Bidshahri R; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Kraft L; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Hwang Y; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Žentelis S; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Jepson KR; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Goya R; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Smith MA; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Collins DW; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Hinshaw SJ; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Tycho SA; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Pellacani D; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Xiang P; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Muthuraman K; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Sobhanifar S; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Piper MH; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA., Triana FJ; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA., Hendle J; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA., Pustilnik A; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA., Adams AC; Eli Lilly and Company, Indianapolis, IN 46225, USA., Berens SJ; Eli Lilly and Company, Indianapolis, IN 46225, USA., Baric RS; University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Martinez DR; University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Cross RW; Galveston National Laboratory and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA., Geisbert TW; Galveston National Laboratory and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA., Borisevich V; Galveston National Laboratory and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA., Abiona O; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Belli HM; Department of Population Health, Division of Biostatistics, New York University Grossman School of Medicine, New York, NY 10016, USA., de Vries M; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Mohamed A; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Dittmann M; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Samanovic MI; NYU Langone Vaccine Center, Department of Medicine, Division of Infectious Diseases and Immunology, New York University Grossman School of Medicine, New York, NY 10016, USA., Mulligan MJ; NYU Langone Vaccine Center, Department of Medicine, Division of Infectious Diseases and Immunology, New York University Grossman School of Medicine, New York, NY 10016, USA., Goldsmith JA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA., Hsieh CL; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA., Johnson NV; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA., Wrapp D; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA., McLellan JS; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA., Barnhart BC; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Graham BS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Hansen CL; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada., Falconer E; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada. jones_bryan_edward@lilly.com ester.falconer@abcellera.com. |
| Source: | Science translational medicine [Sci Transl Med] 2021 May 12; Vol. 13 (593). Date of Electronic Publication: 2021 Apr 05. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 33820835 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Jones+BE%22">Jones BE</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA. jones&#95;bryan&#95;edward@lilly.com ester.falconer@abcellera.com.<br /><searchLink fieldCode="AU" term="%22Brown-Augsburger+PL%22">Brown-Augsburger PL</searchLink>; Eli Lilly and Company, Indianapolis, IN 46225, USA.<br /><searchLink fieldCode="AU" term="%22Corbett+KS%22">Corbett KS</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Westendorf+K%22">Westendorf K</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Davies+J%22">Davies J</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Cujec+TP%22">Cujec TP</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Wiethoff+CM%22">Wiethoff CM</searchLink>; Eli Lilly and Company, Indianapolis, IN 46225, USA.<br /><searchLink fieldCode="AU" term="%22Blackbourne+JL%22">Blackbourne JL</searchLink>; Eli Lilly and Company, Indianapolis, IN 46225, USA.<br /><searchLink fieldCode="AU" term="%22Heinz+BA%22">Heinz BA</searchLink>; Eli Lilly and Company, Indianapolis, IN 46225, USA.<br /><searchLink fieldCode="AU" term="%22Foster+D%22">Foster D</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Higgs+RE%22">Higgs RE</searchLink>; Eli Lilly and Company, Indianapolis, IN 46225, USA.<br /><searchLink fieldCode="AU" term="%22Balasubramaniam+D%22">Balasubramaniam D</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Yang+ES%22">Yang ES</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Bidshahri+R%22">Bidshahri R</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Kraft+L%22">Kraft L</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Hwang+Y%22">Hwang Y</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Žentelis+S%22">Žentelis S</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Jepson+KR%22">Jepson KR</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Goya+R%22">Goya R</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Smith+MA%22">Smith MA</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Collins+DW%22">Collins DW</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Hinshaw+SJ%22">Hinshaw SJ</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Tycho+SA%22">Tycho SA</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Pellacani+D%22">Pellacani D</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Xiang+P%22">Xiang P</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Muthuraman+K%22">Muthuraman K</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Sobhanifar+S%22">Sobhanifar S</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Piper+MH%22">Piper MH</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Triana+FJ%22">Triana FJ</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Hendle+J%22">Hendle J</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Pustilnik+A%22">Pustilnik A</searchLink>; Lilly Biotechnology Center, Eli Lilly and Company, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Adams+AC%22">Adams AC</searchLink>; Eli Lilly and Company, Indianapolis, IN 46225, USA.<br /><searchLink fieldCode="AU" term="%22Berens+SJ%22">Berens SJ</searchLink>; Eli Lilly and Company, Indianapolis, IN 46225, USA.<br /><searchLink fieldCode="AU" term="%22Baric+RS%22">Baric RS</searchLink>; University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+DR%22">Martinez DR</searchLink>; University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Cross+RW%22">Cross RW</searchLink>; Galveston National Laboratory and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Geisbert+TW%22">Geisbert TW</searchLink>; Galveston National Laboratory and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Borisevich+V%22">Borisevich V</searchLink>; Galveston National Laboratory and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Abiona+O%22">Abiona O</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Belli+HM%22">Belli HM</searchLink>; Department of Population Health, Division of Biostatistics, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22de+Vries+M%22">de Vries M</searchLink>; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Mohamed+A%22">Mohamed A</searchLink>; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Dittmann+M%22">Dittmann M</searchLink>; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Samanovic+MI%22">Samanovic MI</searchLink>; NYU Langone Vaccine Center, Department of Medicine, Division of Infectious Diseases and Immunology, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Mulligan+MJ%22">Mulligan MJ</searchLink>; NYU Langone Vaccine Center, Department of Medicine, Division of Infectious Diseases and Immunology, New York University Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Goldsmith+JA%22">Goldsmith JA</searchLink>; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.<br /><searchLink fieldCode="AU" term="%22Hsieh+CL%22">Hsieh CL</searchLink>; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+NV%22">Johnson NV</searchLink>; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.<br /><searchLink fieldCode="AU" term="%22Wrapp+D%22">Wrapp D</searchLink>; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.<br /><searchLink fieldCode="AU" term="%22McLellan+JS%22">McLellan JS</searchLink>; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.<br /><searchLink fieldCode="AU" term="%22Barnhart+BC%22">Barnhart BC</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Graham+BS%22">Graham BS</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Mascola+JR%22">Mascola JR</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Hansen+CL%22">Hansen CL</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada.<br /><searchLink fieldCode="AU" term="%22Falconer+E%22">Falconer E</searchLink>; AbCellera Biologics Inc., Vancouver, BC V5Y0A1, Canada. jones&#95;bryan&#95;edward@lilly.com ester.falconer@abcellera.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2021 May 12; Vol. 13 (593). <i>Date of Electronic Publication: </i>2021 Apr 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/scitranslmed.abf1906 Languages: – Code: eng Text: English Titles: – TitleFull: The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jones BE – PersonEntity: Name: NameFull: Brown-Augsburger PL – PersonEntity: Name: NameFull: Corbett KS – PersonEntity: Name: NameFull: Westendorf K – PersonEntity: Name: NameFull: Davies J – PersonEntity: Name: NameFull: Cujec TP – PersonEntity: Name: NameFull: Wiethoff CM – PersonEntity: Name: NameFull: Blackbourne JL – PersonEntity: Name: NameFull: Heinz BA – PersonEntity: Name: NameFull: Foster D – PersonEntity: Name: NameFull: Higgs RE – PersonEntity: Name: NameFull: Balasubramaniam D – PersonEntity: Name: NameFull: Wang L – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Yang ES – PersonEntity: Name: NameFull: Bidshahri R – PersonEntity: Name: NameFull: Kraft L – PersonEntity: Name: NameFull: Hwang Y – PersonEntity: Name: NameFull: Žentelis S – PersonEntity: Name: NameFull: Jepson KR – PersonEntity: Name: NameFull: Goya R – PersonEntity: Name: NameFull: Smith MA – PersonEntity: Name: NameFull: Collins DW – PersonEntity: Name: NameFull: Hinshaw SJ – PersonEntity: Name: NameFull: Tycho SA – PersonEntity: Name: NameFull: Pellacani D – PersonEntity: Name: NameFull: Xiang P – PersonEntity: Name: NameFull: Muthuraman K – PersonEntity: Name: NameFull: Sobhanifar S – PersonEntity: Name: NameFull: Piper MH – PersonEntity: Name: NameFull: Triana FJ – PersonEntity: Name: NameFull: Hendle J – PersonEntity: Name: NameFull: Pustilnik A – PersonEntity: Name: NameFull: Adams AC – PersonEntity: Name: NameFull: Berens SJ – PersonEntity: Name: NameFull: Baric RS – PersonEntity: Name: NameFull: Martinez DR – PersonEntity: Name: NameFull: Cross RW – PersonEntity: Name: NameFull: Geisbert TW – PersonEntity: Name: NameFull: Borisevich V – PersonEntity: Name: NameFull: Abiona O – PersonEntity: Name: NameFull: Belli HM – PersonEntity: Name: NameFull: de Vries M – PersonEntity: Name: NameFull: Mohamed A – PersonEntity: Name: NameFull: Dittmann M – PersonEntity: Name: NameFull: Samanovic MI – PersonEntity: Name: NameFull: Mulligan MJ – PersonEntity: Name: NameFull: Goldsmith JA – PersonEntity: Name: NameFull: Hsieh CL – PersonEntity: Name: NameFull: Johnson NV – PersonEntity: Name: NameFull: Wrapp D – PersonEntity: Name: NameFull: McLellan JS – PersonEntity: Name: NameFull: Barnhart BC – PersonEntity: Name: NameFull: Graham BS – PersonEntity: Name: NameFull: Mascola JR – PersonEntity: Name: NameFull: Hansen CL – PersonEntity: Name: NameFull: Falconer E IsPartOfRelationships: – BibEntity: Dates: – D: 12 M: 05 Text: 2021 May 12 Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1946-6242 Numbering: – Type: volume Value: 13 – Type: issue Value: 593 Titles: – TitleFull: Science translational medicine Type: main |
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