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Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy.

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Title: Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy.
Authors: Cortellini A; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK alessiocortellini@gmail.com.; Department of Biotechnology and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy., Di Maio M; Department of Oncology and Medical Oncology, University of Turin and AO Ordine Mauriziano, Turin, Italy., Nigro O; Medical Oncology, ASST dei Sette Laghi, Varese, Italy., Leonetti A; Medical Oncology, University Hospital of Parma, Parma, Italy., Cortinovis DL; Medical Oncology, Azienda Ospedaliera San Gerardo, Monza, Italy., Aerts JG; Department of Pulmonary Disease, Erasmus Medical Center, Rotterdam, Netherlands., Guaitoli G; Dipartimento di Oncologia ed Ematologia, AOU Policlinico di Modena, Modena, Italy., Barbieri F; Dipartimento di Oncologia ed Ematologia, AOU Policlinico di Modena, Modena, Italy., Giusti R; Medical Oncology Unit, Sant'Andrea Hospital of Rome, Roma, Italy., Ferrara MG; Comprehensive Cancer Center, Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, Roma, Italy.; Department of Translational Medicine and Surgery, Universitá Cattolica del Sacro Cuore, Roma, Italy., Bria E; Comprehensive Cancer Center, Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, Roma, Italy.; Department of Translational Medicine and Surgery, Universitá Cattolica del Sacro Cuore, Roma, Italy., D'Argento E; Comprehensive Cancer Center, Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, Roma, Italy., Grossi F; Division of Medical Oncology, University of Insubria, Varese, Italy., Rijavec E; Medical Oncology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy., Guida A; Struttura Complessa di Oncologia Medica e Traslazionale, Azienda Ospedaliera Santa Maria di Terni, Terni, Italy., Berardi R; Oncology Clinic, Università Politecnica delle Marche, Ospedali Riuniti di Ancona, Ancona, Italy., Torniai M; Oncology Clinic, Università Politecnica delle Marche, Ospedali Riuniti di Ancona, Ancona, Italy., Sforza V; Thoracic Medical Oncology, National Cancer Institute IRCCS Pascale Foundation, Napoli, Italy., Genova C; Lung Cancer Unit, IRCCS Ospedal Policlinico San Martino, Genova, Italy., Mazzoni F; Department of Medical Oncology, Careggi University Hospital, Firenze, Toscana, Italy., Garassino MC; Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., De Toma A; Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Signorelli D; Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.; Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy., Gelibter A; Medical Oncology Unit B, Policlinico Umberto I, Sapienza University of Rome, Roma, Italy., Siringo M; Medical Oncology Unit B, Policlinico Umberto I, Sapienza University of Rome, Roma, Italy., Marchetti P; Department of Clinical and Molecular Medicine, Sapienza University of Rome, Roma, Italy., Macerelli M; Medical Oncology, University Hospital Santa Maria della Misericordia, Udine, Italy., Rastelli F; Medical Department, ASUR Area Vasta 4, Fermo, Italy., Chiari R; Medical Oncology, Ospedali riuniti Padova Sud 'Madre Teresa Di Calcutta', Monselice, Padova, Italy., Rocco D; Pneumo-Oncology Unit, Ospedali dei Colli Monaldi Cotugno CTO, Napoli, Italy., Della Gravara L; Pneumo-Oncology Unit, Ospedali dei Colli Monaldi Cotugno CTO, Napoli, Italy., Inno A; Oncology Unit, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar, Italy., Michele T; Dipartimento di Terapie Innovative in Medicina ed Odontoiatria, Universitá G. D'Annunzio, Chieti-Pescara, Italy., Grassadonia A; Dipartimento di Terapie Innovative in Medicina ed Odontoiatria, Universitá G. D'Annunzio, Chieti-Pescara, Italy., Di Marino P; Clinical Oncology Unit, SS Annunziata Hospital, Chieti, Italy., Mansueto G; Medical Oncology, Azienda Sanitaria Locale Frosinone, Frosinone, Italy., Zoratto F; Medical Oncology, Ospedale Santa Maria Goretti, Latina, Italy., Filetti M; Medical Oncology Unit, Sant'Andrea Hospital of Rome, Roma, Italy., Santini D; Medical Oncology, Campus Bio-Medico University, Roma, Italy., Citarella F; Medical Oncology, Campus Bio-Medico University, Roma, Italy., Russano M; Medical Oncology, Campus Bio-Medico University, Roma, Italy., Cantini L; Department of Pulmonary Disease, Erasmus Medical Center, Rotterdam, Netherlands.; Oncology Clinic, Università Politecnica delle Marche, Ospedali Riuniti di Ancona, Ancona, Italy., Tuzi A; Medical Oncology, ASST dei Sette Laghi, Varese, Italy., Bordi P; Medical Oncology, University Hospital of Parma, Parma, Italy., Minuti G; Department of Oncology and Hematology, AUSL della Romagna, Ravenna, Italy., Landi L; Department of Oncology and Hematology, AUSL della Romagna, Ravenna, Italy., Ricciardi S; Pneumo-Oncology Unit, San Camillo Forlanini Hospital, Roma, Italy., Migliorino MR; Pneumo-Oncology Unit, San Camillo Forlanini Hospital, Roma, Italy., Passiglia F; Department of Oncology, San Luigi Gonzaga University Hospital, Orbassano, Italy., Bironzo P; Department of Oncology, San Luigi Hospital, Orbassano, Italy., Metro G; Department of Medical Oncology, Santa Maria della Misericordia Hospital, Perugia, Italy., Adamo V; Medical Oncology and Department of Human Pathology, Azienda Ospedaliera Papardo and Università degli Studi di Messina, Messina, Italy., Russo A; Medical Oncology and Department of Human Pathology, Azienda Ospedaliera Papardo and Università degli Studi di Messina, Messina, Italy., Spinelli GP; UOC Territorial Oncology of Aprilia, AUSL Latina, Sapienza University of Rome, Aprilia, Italy., Banna GL; Medical Oncology, Portsmouth University Hospitals NHS Trust, Portsmouth, UK., Friedlaender A; Oncology Department, University Hospital of Geneva, Geneve, Switzerland., Addeo A; Oncology Department, University Hospital of Geneva, Geneve, Switzerland., Cannita K; Medical Oncology, San Salvatore Hospital, L'Aquila, Italy., Ficorella C; Department of Biotechnology and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.; Medical Oncology, San Salvatore Hospital, L'Aquila, Italy., Porzio G; Medical Oncology, San Salvatore Hospital, L'Aquila, Italy., Pinato DJ; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK.; Department of Translational Medicine, Universitá del Piemonte Orientale 'A. Avogadro', Novara, Italy.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 Apr; Vol. 9 (4).
Publication Type: Comparative Study; Journal Article; Multicenter Study
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 33827906
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Cortellini+A%22">Cortellini A</searchLink>; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK alessiocortellini@gmail.com.; Department of Biotechnology and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Maio+M%22">Di Maio M</searchLink>; Department of Oncology and Medical Oncology, University of Turin and AO Ordine Mauriziano, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Nigro+O%22">Nigro O</searchLink>; Medical Oncology, ASST dei Sette Laghi, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Leonetti+A%22">Leonetti A</searchLink>; Medical Oncology, University Hospital of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Cortinovis+DL%22">Cortinovis DL</searchLink>; Medical Oncology, Azienda Ospedaliera San Gerardo, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Aerts+JG%22">Aerts JG</searchLink>; Department of Pulmonary Disease, Erasmus Medical Center, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Guaitoli+G%22">Guaitoli G</searchLink>; Dipartimento di Oncologia ed Ematologia, AOU Policlinico di Modena, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Barbieri+F%22">Barbieri F</searchLink>; Dipartimento di Oncologia ed Ematologia, AOU Policlinico di Modena, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Giusti+R%22">Giusti R</searchLink>; Medical Oncology Unit, Sant'Andrea Hospital of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrara+MG%22">Ferrara MG</searchLink>; Comprehensive Cancer Center, Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, Roma, Italy.; Department of Translational Medicine and Surgery, Universitá Cattolica del Sacro Cuore, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Bria+E%22">Bria E</searchLink>; Comprehensive Cancer Center, Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, Roma, Italy.; Department of Translational Medicine and Surgery, Universitá Cattolica del Sacro Cuore, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22D'Argento+E%22">D'Argento E</searchLink>; Comprehensive Cancer Center, Fondazione Policlinico Universitario 'Agostino Gemelli' IRCCS, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Grossi+F%22">Grossi F</searchLink>; Division of Medical Oncology, University of Insubria, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Rijavec+E%22">Rijavec E</searchLink>; Medical Oncology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Guida+A%22">Guida A</searchLink>; Struttura Complessa di Oncologia Medica e Traslazionale, Azienda Ospedaliera Santa Maria di Terni, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Berardi+R%22">Berardi R</searchLink>; Oncology Clinic, Università Politecnica delle Marche, Ospedali Riuniti di Ancona, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Torniai+M%22">Torniai M</searchLink>; Oncology Clinic, Università Politecnica delle Marche, Ospedali Riuniti di Ancona, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Sforza+V%22">Sforza V</searchLink>; Thoracic Medical Oncology, National Cancer Institute IRCCS Pascale Foundation, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Genova+C%22">Genova C</searchLink>; Lung Cancer Unit, IRCCS Ospedal Policlinico San Martino, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzoni+F%22">Mazzoni F</searchLink>; Department of Medical Oncology, Careggi University Hospital, Firenze, Toscana, Italy.<br /><searchLink fieldCode="AU" term="%22Garassino+MC%22">Garassino MC</searchLink>; Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22De+Toma+A%22">De Toma A</searchLink>; Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Signorelli+D%22">Signorelli D</searchLink>; Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.; Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gelibter+A%22">Gelibter A</searchLink>; Medical Oncology Unit B, Policlinico Umberto I, Sapienza University of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Siringo+M%22">Siringo M</searchLink>; Medical Oncology Unit B, Policlinico Umberto I, Sapienza University of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Marchetti+P%22">Marchetti P</searchLink>; Department of Clinical and Molecular Medicine, Sapienza University of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Macerelli+M%22">Macerelli M</searchLink>; Medical Oncology, University Hospital Santa Maria della Misericordia, Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Rastelli+F%22">Rastelli F</searchLink>; Medical Department, ASUR Area Vasta 4, Fermo, Italy.<br /><searchLink fieldCode="AU" term="%22Chiari+R%22">Chiari R</searchLink>; Medical Oncology, Ospedali riuniti Padova Sud 'Madre Teresa Di Calcutta', Monselice, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Rocco+D%22">Rocco D</searchLink>; Pneumo-Oncology Unit, Ospedali dei Colli Monaldi Cotugno CTO, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Della+Gravara+L%22">Della Gravara L</searchLink>; Pneumo-Oncology Unit, Ospedali dei Colli Monaldi Cotugno CTO, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Inno+A%22">Inno A</searchLink>; Oncology Unit, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar, Italy.<br /><searchLink fieldCode="AU" term="%22Michele+T%22">Michele T</searchLink>; Dipartimento di Terapie Innovative in Medicina ed Odontoiatria, Universitá G. D'Annunzio, Chieti-Pescara, Italy.<br /><searchLink fieldCode="AU" term="%22Grassadonia+A%22">Grassadonia A</searchLink>; Dipartimento di Terapie Innovative in Medicina ed Odontoiatria, Universitá G. D'Annunzio, Chieti-Pescara, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Marino+P%22">Di Marino P</searchLink>; Clinical Oncology Unit, SS Annunziata Hospital, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Mansueto+G%22">Mansueto G</searchLink>; Medical Oncology, Azienda Sanitaria Locale Frosinone, Frosinone, Italy.<br /><searchLink fieldCode="AU" term="%22Zoratto+F%22">Zoratto F</searchLink>; Medical Oncology, Ospedale Santa Maria Goretti, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Filetti+M%22">Filetti M</searchLink>; Medical Oncology Unit, Sant'Andrea Hospital of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Santini+D%22">Santini D</searchLink>; Medical Oncology, Campus Bio-Medico University, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Citarella+F%22">Citarella F</searchLink>; Medical Oncology, Campus Bio-Medico University, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Russano+M%22">Russano M</searchLink>; Medical Oncology, Campus Bio-Medico University, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Cantini+L%22">Cantini L</searchLink>; Department of Pulmonary Disease, Erasmus Medical Center, Rotterdam, Netherlands.; Oncology Clinic, Università Politecnica delle Marche, Ospedali Riuniti di Ancona, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Tuzi+A%22">Tuzi A</searchLink>; Medical Oncology, ASST dei Sette Laghi, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Bordi+P%22">Bordi P</searchLink>; Medical Oncology, University Hospital of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Minuti+G%22">Minuti G</searchLink>; Department of Oncology and Hematology, AUSL della Romagna, Ravenna, Italy.<br /><searchLink fieldCode="AU" term="%22Landi+L%22">Landi L</searchLink>; Department of Oncology and Hematology, AUSL della Romagna, Ravenna, Italy.<br /><searchLink fieldCode="AU" term="%22Ricciardi+S%22">Ricciardi S</searchLink>; Pneumo-Oncology Unit, San Camillo Forlanini Hospital, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Migliorino+MR%22">Migliorino MR</searchLink>; Pneumo-Oncology Unit, San Camillo Forlanini Hospital, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Passiglia+F%22">Passiglia F</searchLink>; Department of Oncology, San Luigi Gonzaga University Hospital, Orbassano, Italy.<br /><searchLink fieldCode="AU" term="%22Bironzo+P%22">Bironzo P</searchLink>; Department of Oncology, San Luigi Hospital, Orbassano, Italy.<br /><searchLink fieldCode="AU" term="%22Metro+G%22">Metro G</searchLink>; Department of Medical Oncology, Santa Maria della Misericordia Hospital, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Adamo+V%22">Adamo V</searchLink>; Medical Oncology and Department of Human Pathology, Azienda Ospedaliera Papardo and Università degli Studi di Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Russo+A%22">Russo A</searchLink>; Medical Oncology and Department of Human Pathology, Azienda Ospedaliera Papardo and Università degli Studi di Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Spinelli+GP%22">Spinelli GP</searchLink>; UOC Territorial Oncology of Aprilia, AUSL Latina, Sapienza University of Rome, Aprilia, Italy.<br /><searchLink fieldCode="AU" term="%22Banna+GL%22">Banna GL</searchLink>; Medical Oncology, Portsmouth University Hospitals NHS Trust, Portsmouth, UK.<br /><searchLink fieldCode="AU" term="%22Friedlaender+A%22">Friedlaender A</searchLink>; Oncology Department, University Hospital of Geneva, Geneve, Switzerland.<br /><searchLink fieldCode="AU" term="%22Addeo+A%22">Addeo A</searchLink>; Oncology Department, University Hospital of Geneva, Geneve, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cannita+K%22">Cannita K</searchLink>; Medical Oncology, San Salvatore Hospital, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Ficorella+C%22">Ficorella C</searchLink>; Department of Biotechnology and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.; Medical Oncology, San Salvatore Hospital, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Porzio+G%22">Porzio G</searchLink>; Medical Oncology, San Salvatore Hospital, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Pinato+DJ%22">Pinato DJ</searchLink>; Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK.; Department of Translational Medicine, Universitá del Piemonte Orientale 'A. Avogadro', Novara, Italy.
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            NameFull: Tuzi A
      – PersonEntity:
          Name:
            NameFull: Bordi P
      – PersonEntity:
          Name:
            NameFull: Minuti G
      – PersonEntity:
          Name:
            NameFull: Landi L
      – PersonEntity:
          Name:
            NameFull: Ricciardi S
      – PersonEntity:
          Name:
            NameFull: Migliorino MR
      – PersonEntity:
          Name:
            NameFull: Passiglia F
      – PersonEntity:
          Name:
            NameFull: Bironzo P
      – PersonEntity:
          Name:
            NameFull: Metro G
      – PersonEntity:
          Name:
            NameFull: Adamo V
      – PersonEntity:
          Name:
            NameFull: Russo A
      – PersonEntity:
          Name:
            NameFull: Spinelli GP
      – PersonEntity:
          Name:
            NameFull: Banna GL
      – PersonEntity:
          Name:
            NameFull: Friedlaender A
      – PersonEntity:
          Name:
            NameFull: Addeo A
      – PersonEntity:
          Name:
            NameFull: Cannita K
      – PersonEntity:
          Name:
            NameFull: Ficorella C
      – PersonEntity:
          Name:
            NameFull: Porzio G
      – PersonEntity:
          Name:
            NameFull: Pinato DJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: 2021 Apr
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 2051-1426
          Numbering:
            – Type: volume
              Value: 9
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Journal for immunotherapy of cancer
              Type: main
ResultId 1