The NIH Somatic Cell Genome Editing program.
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| Title: | The NIH Somatic Cell Genome Editing program. |
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| Authors: | Saha K; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA. ksaha@wisc.edu.; Department of Medical History & Bioethics, University of Wisconsin-Madison, Madison, WI, USA. ksaha@wisc.edu.; Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA. ksaha@wisc.edu.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA. ksaha@wisc.edu., Sontheimer EJ; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA. erik.sontheimer@umassmed.edu., Brooks PJ; Office of Rare Diseases Research, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Bethesda, MD, USA., Dwinell MR; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA., Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Liu DR; Merkin Institute of Transformative Technologies, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Murray SA; The Jackson Laboratory, Bar Harbor, ME, USA., Tsai SQ; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA., Wilson RC; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Anderson DG; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology, Cambridge, MA, USA., Asokan A; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, USA., Banfield JF; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, Berkeley, CA, USA., Bankiewicz KS; Department of Neurological Surgery, Ohio State University, Columbus, OH, USA., Bao G; Department of Bioengineering, Rice University, Houston, TX, USA., Bulte JWM; Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Cellular Imaging Section and Vascular Biology Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Bursac N; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Campbell JM; Recombinetics, Inc, Eagan, MN, USA., Carlson DF; Recombinetics, Inc, Eagan, MN, USA., Chaikof EL; Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA., Chen ZY; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, USA.; Program in Neuroscience, Harvard Medical School, Boston, MA, USA.; Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA, USA., Cheng RH; Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA, USA., Clark KJ; Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester, Rochester, MN, USA., Curiel DT; Department of Radiation Oncology, Washington University in St Louis, St Louis, MO, USA., Dahlman JE; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Deverman BE; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA., Dickinson ME; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Doudna JA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.; Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA., Ekker SC; Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester, Rochester, MN, USA., Emborg ME; Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Feng G; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Freedman BS; Division of Nephrology, University of Washington, Seattle, WA, USA.; Kidney Research Institute, University of Washington, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA., Gamm DM; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Gao G; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA, USA., Ghiran IC; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Glazer PM; Department of Therapeutic Radiology, Yale University, New Haven, CT, USA., Gong S; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA., Heaney JD; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Hennebold JD; Division of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA., Hinson JT; Pat and Jim Calhoun Cardiology Center, University of Connecticut School of Medicine, Farmington, CT, USA., Khvorova A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA., Kiani S; Pittsburgh Liver Research Center, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Lagor WR; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Lam KS; Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, USA., Leong KW; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Levine JE; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Lewis JA; Wyss Institute, Harvard University, Cambridge, MA, USA., Lutz CM; The Jackson Laboratory, Bar Harbor, ME, USA., Ly DH; Department of Chemistry, Carnegie-Mellon University, Pittsburgh, PA, USA., Maragh S; Biomarker and Genomic Sciences Group, National Institute of Standards and Technology, Gaithersburg, MD, USA., McCray PB Jr; Department of Pediatrics, University of Iowa, Iowa City, IA, USA., McDevitt TC; Gladstone Institute of Cardiovascular Disease, Gladstone Institutes, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA., Mirochnitchenko O; Office of Research Infrastructure Programs, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA., Morizane R; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Murthy N; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Prather RS; Division of Animal Sciences, University of Missouri, Columbia, MO, USA., Ronald JA; Robarts Research Institute and Department of Medical Biophysics, The University of Western Ontario, London, Ontario, Canada., Roy S; Department of Pathology, University of California, San Diego, La Jolla, CA, USA., Roy S; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA.; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA., Sabbisetti V; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Saltzman WM; Department of Biomedical Engineering, Yale University, New Haven, CT, USA., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Segal DJ; Department of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, USA., Shimoyama M; Department of Biomedical Engineering, Marquette University and Medical College of Wisconsin, Milwaukee, WI, USA., Skala MC; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA., Tarantal AF; Department of Pediatrics, University of California, Davis, Davis, CA, USA.; Department of Cell Biology and Human Anatomy, University of California, Davis, Davis, CA, USA.; School of Medicine, University of California, Davis, Davis, CA, USA.; California National Primate Research Center, University of California, Davis, Davis, CA, USA., Tilton JC; Department of Nutrition, Case Western Reserve University, Cleveland, OH, USA., Truskey GA; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Vandsburger M; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Watts JK; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA., Wells KD; Division of Animal Sciences, University of Missouri, Columbia, MO, USA., Wolfe SA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, Worcester, MA, USA., Xu Q; Department of Biomedical Engineering, Tufts University, Medford, MA, USA., Xue W; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA., Yi G; Department of Pulmonary Immunology, University of Texas Health Sciences Center at Tyler, Tyler, TX, USA., Zhou J; Department of Neurosurgery, Yale University, New Haven, CT, USA. |
| Corporate Authors: | SCGE Consortium |
| Source: | Nature [Nature] 2021 Apr; Vol. 592 (7853), pp. 195-204. Date of Electronic Publication: 2021 Apr 07. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Review |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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