Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
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| Title: | Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study. |
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| Authors: | Ibrahim TS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt. Electronic address: tmabrahem@kau.edu.sa., Almalki AJ; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Moustafa AH; Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt., Allam RM; Pharmacology Department, National Research Centre, Cairo 12622 (ID: 60014618), Egypt., Abuo-Rahma GEA; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Deraya University, New Minia, Minia, Egypt., El Subbagh HI; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt., Mohamed MFA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, 82524 Sohag, Egypt. Electronic address: mamdouh.fawzi@pharm.sohag.edu.eg. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2021 Jun; Vol. 111, pp. 104885. Date of Electronic Publication: 2021 Apr 01. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 33838559 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ibrahim+TS%22">Ibrahim TS</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt. Electronic address: tmabrahem@kau.edu.sa.<br /><searchLink fieldCode="AU" term="%22Almalki+AJ%22">Almalki AJ</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Moustafa+AH%22">Moustafa AH</searchLink>; Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt.<br /><searchLink fieldCode="AU" term="%22Allam+RM%22">Allam RM</searchLink>; Pharmacology Department, National Research Centre, Cairo 12622 (ID: 60014618), Egypt.<br /><searchLink fieldCode="AU" term="%22Abuo-Rahma+GEA%22">Abuo-Rahma GEA</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Deraya University, New Minia, Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22El+Subbagh+HI%22">El Subbagh HI</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohamed+MFA%22">Mohamed MFA</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, 82524 Sohag, Egypt. Electronic address: mamdouh.fawzi@pharm.sohag.edu.eg. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2021 Jun; Vol. 111, pp. 104885. <i>Date of Electronic Publication: </i>2021 Apr 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33838559 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bioorg.2021.104885 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 104885 Titles: – TitleFull: Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ibrahim TS – PersonEntity: Name: NameFull: Almalki AJ – PersonEntity: Name: NameFull: Moustafa AH – PersonEntity: Name: NameFull: Allam RM – PersonEntity: Name: NameFull: Abuo-Rahma GEA – PersonEntity: Name: NameFull: El Subbagh HI – PersonEntity: Name: NameFull: Mohamed MFA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2021 Jun Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1090-2120 Numbering: – Type: volume Value: 111 Titles: – TitleFull: Bioorganic chemistry Type: main |
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