Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.

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Title: Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.
Authors: Ehteda A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Simon S; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Franshaw L; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Giorgi FM; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy., Liu J; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Joshi S; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Rouaen JRC; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Pang CNI; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia., Pandher R; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Mayoh C; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia., Tang Y; State Key Laboratory of Oncogenes and Related Genes, Key Laboratory of Cell Differentiation and Apoptosis of National Ministry of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China., Khan A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Ung C; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Tolhurst O; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Kankean A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Hayden E; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Lehmann R; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Shen S; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Gopalakrishnan A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Trebilcock P; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Gurova K; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Gudkov AV; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Norris MD; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; Centre for Childhood Cancer Research, University of New South Wales, Sydney, NSW, Australia., Haber M; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Vittorio O; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia., Tsoli M; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia. Electronic address: mtsoli@ccia.org.au., Ziegler DS; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia; Kid's Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia. Electronic address: d.ziegler@unsw.edu.au.
Source: Cell reports [Cell Rep] 2021 Apr 13; Vol. 35 (2), pp. 108994.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.
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  Data: <searchLink fieldCode="AU" term="%22Ehteda+A%22">Ehteda A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Simon+S%22">Simon S</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Franshaw+L%22">Franshaw L</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Giorgi+FM%22">Giorgi FM</searchLink>; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Joshi+S%22">Joshi S</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Rouaen+JRC%22">Rouaen JRC</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Pang+CNI%22">Pang CNI</searchLink>; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Pandher+R%22">Pandher R</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Mayoh+C%22">Mayoh C</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Tang+Y%22">Tang Y</searchLink>; State Key Laboratory of Oncogenes and Related Genes, Key Laboratory of Cell Differentiation and Apoptosis of National Ministry of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.<br /><searchLink fieldCode="AU" term="%22Khan+A%22">Khan A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Ung+C%22">Ung C</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Tolhurst+O%22">Tolhurst O</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Kankean+A%22">Kankean A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Hayden+E%22">Hayden E</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Lehmann+R%22">Lehmann R</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Shen+S%22">Shen S</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Gopalakrishnan+A%22">Gopalakrishnan A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Trebilcock+P%22">Trebilcock P</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Gurova+K%22">Gurova K</searchLink>; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gudkov+AV%22">Gudkov AV</searchLink>; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.<br /><searchLink fieldCode="AU" term="%22Norris+MD%22">Norris MD</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; Centre for Childhood Cancer Research, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Haber+M%22">Haber M</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Vittorio+O%22">Vittorio O</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Tsoli+M%22">Tsoli M</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia. Electronic address: mtsoli@ccia.org.au.<br /><searchLink fieldCode="AU" term="%22Ziegler+DS%22">Ziegler DS</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia; Kid's Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia. Electronic address: d.ziegler@unsw.edu.au.
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