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Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction.

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Title: Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction.
Authors: Beshore DC; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Adam GC; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Barnard RJO; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Burlein C; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Gallicchio SN; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Holloway MK; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Krosky D; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Lemaire W; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Myers RW; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Patel S; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Plotkin MA; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Powell DA; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Rada V; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Cox CD; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Coleman PJ; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Klein DJ; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Wolkenberg SE; MRL, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Mar 07; Vol. 12 (4), pp. 540-547. Date of Electronic Publication: 2021 Mar 07 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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