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Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation.

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Title: Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation.
Authors: Hoang VT; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA., Matossian MD; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA., La J; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA., Hoang K; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA., Ucar DA; Department of Genetics and Stanley S. Scott Cancer Center, LSUHSC, New Orleans, Louisiana, USA., Elliott S; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA., Burks HE; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA., Wright TD; Department of Pharmacology, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA., Patel S; Department of Pharmacology, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA., Bhatt A; Department of Pharmacology, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA., Phamduy T; Department of Physics, Tulane University, New Orleans, Louisiana, USA., Chrisey D; Department of Physics, Tulane University, New Orleans, Louisiana, USA., Buechlein A; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, Indiana, USA., Rusch DB; Center for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA., Nephew KP; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, Indiana, USA., Anbalagan M; Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA., Rowan B; Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA., Cavanaugh JE; Department of Pharmacology, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA., Flaherty PT; Department of Medicinal Chemistry, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA., Miele L; Department of Genetics and Stanley S. Scott Cancer Center, LSUHSC, New Orleans, Louisiana, USA., Collins-Burow BM; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.; Tulane Cancer Center, New Orleans, Louisiana, USA., Burow ME; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Source: Journal of cellular biochemistry [J Cell Biochem] 2021 Aug; Vol. 122 (8), pp. 835-850. Date of Electronic Publication: 2021 Apr 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8205768 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4644 (Electronic) Linking ISSN: 07302312 NLM ISO Abbreviation: J Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation.
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  Data: <searchLink fieldCode="AU" term="%22Hoang+VT%22">Hoang VT</searchLink>; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Matossian+MD%22">Matossian MD</searchLink>; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22La+J%22">La J</searchLink>; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Hoang+K%22">Hoang K</searchLink>; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Ucar+DA%22">Ucar DA</searchLink>; Department of Genetics and Stanley S. Scott Cancer Center, LSUHSC, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Elliott+S%22">Elliott S</searchLink>; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Burks+HE%22">Burks HE</searchLink>; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Wright+TD%22">Wright TD</searchLink>; Department of Pharmacology, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Patel+S%22">Patel S</searchLink>; Department of Pharmacology, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Bhatt+A%22">Bhatt A</searchLink>; Department of Pharmacology, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Phamduy+T%22">Phamduy T</searchLink>; Department of Physics, Tulane University, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Chrisey+D%22">Chrisey D</searchLink>; Department of Physics, Tulane University, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Buechlein+A%22">Buechlein A</searchLink>; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Rusch+DB%22">Rusch DB</searchLink>; Center for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Nephew+KP%22">Nephew KP</searchLink>; Medical Sciences Program, Indiana University School of Medicine-Bloomington, Bloomington, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Anbalagan+M%22">Anbalagan M</searchLink>; Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Rowan+B%22">Rowan B</searchLink>; Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Cavanaugh+JE%22">Cavanaugh JE</searchLink>; Department of Pharmacology, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Flaherty+PT%22">Flaherty PT</searchLink>; Department of Medicinal Chemistry, Duquesne University, School of Pharmacy, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Miele+L%22">Miele L</searchLink>; Department of Genetics and Stanley S. Scott Cancer Center, LSUHSC, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Collins-Burow+BM%22">Collins-Burow BM</searchLink>; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.; Tulane Cancer Center, New Orleans, Louisiana, USA.<br /><searchLink fieldCode="AU" term="%22Burow+ME%22">Burow ME</searchLink>; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
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  Data: <searchLink fieldCode="JN" term="%228205768%22">Journal of cellular biochemistry</searchLink> [J Cell Biochem] 2021 Aug; Vol. 122 (8), pp. 835-850. <i>Date of Electronic Publication: </i>2021 Apr 20.
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