Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M1 -acetylcholine receptor agonist: A randomized cross-over trial.
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| Title: | Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M |
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| Authors: | Bakker C; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands., Prins S; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands., Liptrot J; Sosei Heptares, Cambridge, UK., Hart EP; Centre for Human Drug Research, Leiden, The Netherlands., Klaassen ES; Centre for Human Drug Research, Leiden, The Netherlands., Brown GA; Sosei Heptares, Cambridge, UK., Brown A; Sosei Heptares, Cambridge, UK., Congreve M; Sosei Heptares, Cambridge, UK., Weir M; Sosei Heptares, Cambridge, UK., Marshall FH; Sosei Heptares, Cambridge, UK.; MSD Research Laboratories (Merck & Co), Kenilworth, New Jersey, USA., Stevens J; Centre for Human Drug Research, Leiden, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Cross DM; Cross Pharma Consulting Ltd, Cambridge, UK., Tasker T; Sosei Heptares, Cambridge, UK., Nathan PJ; Sosei Heptares, Cambridge, UK.; Department of Psychiatry, University of Cambridge, Cambridge, UK.; School of Psychological Sciences, Monash University, Australia., Groeneveld GJ; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands. |
| Source: | British journal of clinical pharmacology [Br J Clin Pharmacol] 2021 Nov; Vol. 87 (11), pp. 4439-4449. Date of Electronic Publication: 2021 May 08. |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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