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Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.

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Title: Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
Authors: Larraufie MH; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Gao X; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Xia X; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Devine PJ; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Kallen J; Novartis Institutes for Biomedical Research, Basel, Switzerland., Liu D; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Michaud G; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Harsch A; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Savage N; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Ding J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Tan K; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Mihalic M; Novartis Institutes for Biomedical Research, Basel, Switzerland., Roggo S; Novartis Institutes for Biomedical Research, Basel, Switzerland., Canham SM; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Bushell SM; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Krastel P; Novartis Institutes for Biomedical Research, Basel, Switzerland., Gao J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Izaac A; Novartis Institutes for Biomedical Research, Basel, Switzerland., Altinoglu E; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Lustenberger P; Novartis Global Drug Development, Basel, Switzerland., Salcius M; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Harbinski F; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Williams ET; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Zeng L; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Loureiro J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Cong F; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Fryer CJ; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Klickstein L; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Tallarico JA; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Jain RK; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Rothman DM; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Wang S; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. Electronic address: shaowen.wang@novartis.com.
Source: Cell chemical biology [Cell Chem Biol] 2021 Sep 16; Vol. 28 (9), pp. 1271-1282.e12. Date of Electronic Publication: 2021 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
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  Data: <searchLink fieldCode="AU" term="%22Larraufie+MH%22">Larraufie MH</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Xia+X%22">Xia X</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Devine+PJ%22">Devine PJ</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kallen+J%22">Kallen J</searchLink>; Novartis Institutes for Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Michaud+G%22">Michaud G</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Harsch+A%22">Harsch A</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Savage+N%22">Savage N</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ding+J%22">Ding J</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tan+K%22">Tan K</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mihalic+M%22">Mihalic M</searchLink>; Novartis Institutes for Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Roggo+S%22">Roggo S</searchLink>; Novartis Institutes for Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Canham+SM%22">Canham SM</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bushell+SM%22">Bushell SM</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Krastel+P%22">Krastel P</searchLink>; Novartis Institutes for Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gao+J%22">Gao J</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Izaac+A%22">Izaac A</searchLink>; Novartis Institutes for Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Altinoglu+E%22">Altinoglu E</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lustenberger+P%22">Lustenberger P</searchLink>; Novartis Global Drug Development, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Salcius+M%22">Salcius M</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Harbinski+F%22">Harbinski F</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Williams+ET%22">Williams ET</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zeng+L%22">Zeng L</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Loureiro+J%22">Loureiro J</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cong+F%22">Cong F</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fryer+CJ%22">Fryer CJ</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Klickstein+L%22">Klickstein L</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tallarico+JA%22">Tallarico JA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jain+RK%22">Jain RK</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rothman+DM%22">Rothman DM</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. Electronic address: shaowen.wang@novartis.com.
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  Data: <searchLink fieldCode="JN" term="%22101676030%22">Cell chemical biology</searchLink> [Cell Chem Biol] 2021 Sep 16; Vol. 28 (9), pp. 1271-1282.e12. <i>Date of Electronic Publication: </i>2021 Apr 23.
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