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Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series.

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Title: Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series.
Authors: Truong TT; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Ryutov A; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Pandey U; Department of Pathology, Westchester Medical Center/New York Medical College, Valhalla, NY, United States., Yee R; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Goldberg L; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Bhojwani D; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Aguayo-Hiraldo P; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; Department of Pediatrics, Cancer and Blood Disorder Institute, Transplant and Cellular Therapy Section, Children's Hospital Los Angeles, CA, United States., Pinsky BA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Pekosz A; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Shen L; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Boyd SD; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States; Sean N. Parker Center for Allergy and Asthma Research, Stanford, CA, United States., Wirz OF; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States., Röltgen K; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States., Bootwalla M; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Maglinte DT; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Ostrow D; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Ruble D; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Han JH; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States., Biegel JA; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Li M; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Huang C; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States., Sahoo MK; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States., Pannaraj PS; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; Department of Pediatrics, Division of Infectious Diseases, Children's Hospital Los Angeles, Los Angeles, CA, United States., O'Gorman M; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Judkins AR; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Gai X; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Dien Bard J; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address: jdienbard@chla.usc.edu.
Source: EBioMedicine [EBioMedicine] 2021 May; Vol. 67, pp. 103355. Date of Electronic Publication: 2021 Apr 26.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series.
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  Data: <searchLink fieldCode="AU" term="%22Truong+TT%22">Truong TT</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Ryutov+A%22">Ryutov A</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Pandey+U%22">Pandey U</searchLink>; Department of Pathology, Westchester Medical Center/New York Medical College, Valhalla, NY, United States.<br /><searchLink fieldCode="AU" term="%22Yee+R%22">Yee R</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Goldberg+L%22">Goldberg L</searchLink>; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Bhojwani+D%22">Bhojwani D</searchLink>; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Aguayo-Hiraldo+P%22">Aguayo-Hiraldo P</searchLink>; Department of Pediatrics, Cancer and Blood Disease Institute, Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; Department of Pediatrics, Cancer and Blood Disorder Institute, Transplant and Cellular Therapy Section, Children's Hospital Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Pinsky+BA%22">Pinsky BA</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Pekosz+A%22">Pekosz A</searchLink>; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.<br /><searchLink fieldCode="AU" term="%22Shen+L%22">Shen L</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Boyd+SD%22">Boyd SD</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States; Sean N. Parker Center for Allergy and Asthma Research, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Wirz+OF%22">Wirz OF</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Röltgen+K%22">Röltgen K</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Bootwalla+M%22">Bootwalla M</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Maglinte+DT%22">Maglinte DT</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Ostrow+D%22">Ostrow D</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Ruble+D%22">Ruble D</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Han+JH%22">Han JH</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Biegel+JA%22">Biegel JA</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.<br /><searchLink fieldCode="AU" term="%22Huang+C%22">Huang C</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Sahoo+MK%22">Sahoo MK</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Pannaraj+PS%22">Pannaraj PS</searchLink>; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States; Department of Pediatrics, Division of Infectious Diseases, Children's Hospital Los Angeles, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22O'Gorman+M%22">O'Gorman M</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Judkins+AR%22">Judkins AR</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Gai+X%22">Gai X</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.<br /><searchLink fieldCode="AU" term="%22Dien+Bard+J%22">Dien Bard J</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States; Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address: jdienbard@chla.usc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101647039%22">EBioMedicine</searchLink> [EBioMedicine] 2021 May; Vol. 67, pp. 103355. <i>Date of Electronic Publication: </i>2021 Apr 26.
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