A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.
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| Title: | A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions. |
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| Authors: | Frechen S; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Solodenko J; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Wendl T; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Dallmann A; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Ince I; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Lehr T; Clinical Pharmacy, Saarland University, Saarbrücken, Germany., Lippert J; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Burghaus R; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany. |
| Source: | CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2021 Jun; Vol. 10 (6), pp. 633-644. Date of Electronic Publication: 2021 May 24. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 33946131 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Frechen+S%22">Frechen S</searchLink>; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Solodenko+J%22">Solodenko J</searchLink>; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Wendl+T%22">Wendl T</searchLink>; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Dallmann+A%22">Dallmann A</searchLink>; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Ince+I%22">Ince I</searchLink>; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Lehr+T%22">Lehr T</searchLink>; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Lippert+J%22">Lippert J</searchLink>; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Burghaus+R%22">Burghaus R</searchLink>; Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101580011%22">CPT: pharmacometrics & systems pharmacology</searchLink> [CPT Pharmacometrics Syst Pharmacol] 2021 Jun; Vol. 10 (6), pp. 633-644. <i>Date of Electronic Publication: </i>2021 May 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101580011 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2163-8306 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221638306%22">21638306 </searchLink><i>NLM ISO Abbreviation: </i>CPT Pharmacometrics Syst Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33946131 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/psp4.12636 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 633 Titles: – TitleFull: A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Frechen S – PersonEntity: Name: NameFull: Solodenko J – PersonEntity: Name: NameFull: Wendl T – PersonEntity: Name: NameFull: Dallmann A – PersonEntity: Name: NameFull: Ince I – PersonEntity: Name: NameFull: Lehr T – PersonEntity: Name: NameFull: Lippert J – PersonEntity: Name: NameFull: Burghaus R IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2021 Jun Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 2163-8306 Numbering: – Type: volume Value: 10 – Type: issue Value: 6 Titles: – TitleFull: CPT: pharmacometrics & systems pharmacology Type: main |
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