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SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD-mutant AML.

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Title: SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD-mutant AML.
Authors: Pacharne S; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Dovey OM; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Cooper JL; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Gu M; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Friedrich MJ; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany., Rajan SS; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; United Kingdom Dementia Research Institute, University of Cambridge, Cambridge, United Kingdom., Barenboim M; Department of Pediatrics and Children's Cancer Research Center, Klinikum Rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany., Collord G; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Vijayabaskar MS; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Ponstingl H; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., De Braekeleer E; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Bautista R; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom., Mazan M; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Research and Development Department, Selvita S.A., Krakow, Poland., Rad R; Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; and., Tzelepis K; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Gurdon Institute.; Department of Pathology, and., Wright P; Department of Pathology, and., Gozdecka M; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Vassiliou GS; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, Cambridge University Hospitals National Health Service (NHS) Trust, Cambridge, United Kingdom.
Source: Blood advances [Blood Adv] 2021 May 11; Vol. 5 (9), pp. 2412-2425.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD-mutant AML.
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  Data: <searchLink fieldCode="AU" term="%22Pacharne+S%22">Pacharne S</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dovey+OM%22">Dovey OM</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cooper+JL%22">Cooper JL</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gu+M%22">Gu M</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Friedrich+MJ%22">Friedrich MJ</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Rajan+SS%22">Rajan SS</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; United Kingdom Dementia Research Institute, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Barenboim+M%22">Barenboim M</searchLink>; Department of Pediatrics and Children's Cancer Research Center, Klinikum Rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Collord+G%22">Collord G</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Vijayabaskar+MS%22">Vijayabaskar MS</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ponstingl+H%22">Ponstingl H</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22De+Braekeleer+E%22">De Braekeleer E</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bautista+R%22">Bautista R</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mazan+M%22">Mazan M</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Research and Development Department, Selvita S.A., Krakow, Poland.<br /><searchLink fieldCode="AU" term="%22Rad+R%22">Rad R</searchLink>; Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; and.<br /><searchLink fieldCode="AU" term="%22Tzelepis+K%22">Tzelepis K</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Gurdon Institute.; Department of Pathology, and.<br /><searchLink fieldCode="AU" term="%22Wright+P%22">Wright P</searchLink>; Department of Pathology, and.<br /><searchLink fieldCode="AU" term="%22Gozdecka+M%22">Gozdecka M</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Vassiliou+GS%22">Vassiliou GS</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom.; Wellcome-Medical Research Center (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, Cambridge University Hospitals National Health Service (NHS) Trust, Cambridge, United Kingdom.
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        Value: 10.1182/bloodadvances.2020003443
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        Text: English
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