SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD-mutant AML. - Pacharne S; Dovey OM; Cooper JL; Gu M; Friedrich MJ; Rajan SS; Barenboim M; Collord G; Vijayabaskar MS; Ponstingl H; De Braekeleer E; Bautista R; et al. (Blood advances, 2021)