Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial.
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| Title: | Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. |
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| Authors: | Rovin BH; Department of Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Teng YKO; Department of Nephrology, Leiden University Medical Centre, Leiden, The Netherlands., Ginzler EM; Department of Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY, USA., Arriens C; Department of Arthritis & Clinical Immunology, Rheumatology, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Caster DJ; Department of Medicine, Division of Nephrology and Hypertension, University of Louisville School of Medicine, Louisville, KY, USA., Romero-Diaz J; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico., Gibson K; Department of Medicine, UNC Kidney Center, Chapel Hill, NC, United States., Kaplan J; Department of Medicine, Rutgers University, Newark, NJ, USA., Lisk L; Clinical Development, Aurinia Pharmaceuticals, Victoria, BC, Canada., Navarra S; University of Santo Tomas, Manila and St Luke's Medical Center, Quezon City, Philippines., Parikh SV; Department of Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Randhawa S; Clinical Development, Aurinia Pharmaceuticals, Victoria, BC, Canada., Solomons N; Clinical Development, Aurinia Pharmaceuticals, Victoria, BC, Canada., Huizinga RB; Research, Aurinia Pharmaceuticals, Victoria, BC, Canada. Electronic address: rhuizinga@auriniapharma.com. |
| Source: | Lancet (London, England) [Lancet] 2021 May 29; Vol. 397 (10289), pp. 2070-2080. Date of Electronic Publication: 2021 May 07. |
| Publication Type: | Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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