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A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy.

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Title: A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy.
Authors: Hsu EJ; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Cao X; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Xuezhi.Cao@UTSouthwestern.edu., Moon B; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Bae J; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Sun Z; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.; Department of Biomedical Engineering, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Liu Z; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Fu YX; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Yang-Xin.Fu@UTSouthwestern.edu.; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Yang-Xin.Fu@UTSouthwestern.edu.
Source: Nature communications [Nat Commun] 2021 May 13; Vol. 12 (1), pp. 2768. Date of Electronic Publication: 2021 May 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy.
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  Data: <searchLink fieldCode="AU" term="%22Hsu+EJ%22">Hsu EJ</searchLink>; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.<br /><searchLink fieldCode="AU" term="%22Cao+X%22">Cao X</searchLink>; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Xuezhi.Cao@UTSouthwestern.edu.<br /><searchLink fieldCode="AU" term="%22Moon+B%22">Moon B</searchLink>; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.<br /><searchLink fieldCode="AU" term="%22Bae+J%22">Bae J</searchLink>; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.<br /><searchLink fieldCode="AU" term="%22Sun+Z%22">Sun Z</searchLink>; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.; Department of Biomedical Engineering, UT Southwestern Medical Center, Dallas, TX, 75390, USA.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.<br /><searchLink fieldCode="AU" term="%22Fu+YX%22">Fu YX</searchLink>; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Yang-Xin.Fu@UTSouthwestern.edu.; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Yang-Xin.Fu@UTSouthwestern.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2021 May 13; Vol. 12 (1), pp. 2768. <i>Date of Electronic Publication: </i>2021 May 13.
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