A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy.
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| Title: | A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy. |
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| Authors: | Hsu EJ; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Cao X; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Xuezhi.Cao@UTSouthwestern.edu., Moon B; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Bae J; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Sun Z; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.; Department of Biomedical Engineering, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Liu Z; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA., Fu YX; Department of Immunology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Yang-Xin.Fu@UTSouthwestern.edu.; Department of Pathology, UT Southwestern Medical Center, Dallas, TX, 75390, USA. Yang-Xin.Fu@UTSouthwestern.edu. |
| Source: | Nature communications [Nat Commun] 2021 May 13; Vol. 12 (1), pp. 2768. Date of Electronic Publication: 2021 May 13. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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