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Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cell killing in combination with PD1/PDL1 blockade and HER2 inhibition.

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Title: Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cell killing in combination with PD1/PDL1 blockade and HER2 inhibition.
Authors: Gu CL; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China., Zhu HX; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China., Deng L; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China., Meng XQ; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China., Li K; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China., Xu W; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China., Zhao L; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China., Liu YQ; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China., Zhu ZP; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China. zhuzhenping@3sbio.com., Huang HM; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China. huanghaomin@3s-guojian.com.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2022 Mar; Vol. 43 (3), pp. 672-680. Date of Electronic Publication: 2021 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cell killing in combination with PD1/PDL1 blockade and HER2 inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Gu+CL%22">Gu CL</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China.<br /><searchLink fieldCode="AU" term="%22Zhu+HX%22">Zhu HX</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China.<br /><searchLink fieldCode="AU" term="%22Deng+L%22">Deng L</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China.<br /><searchLink fieldCode="AU" term="%22Meng+XQ%22">Meng XQ</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China.<br /><searchLink fieldCode="AU" term="%22Li+K%22">Li K</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China.<br /><searchLink fieldCode="AU" term="%22Xu+W%22">Xu W</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China.<br /><searchLink fieldCode="AU" term="%22Liu+YQ%22">Liu YQ</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China.<br /><searchLink fieldCode="AU" term="%22Zhu+ZP%22">Zhu ZP</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China. zhuzhenping@3sbio.com.<br /><searchLink fieldCode="AU" term="%22Huang+HM%22">Huang HM</searchLink>; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd., 3SBio Inc. Company, Shanghai, 201203, China. huanghaomin@3s-guojian.com.
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  Data: <searchLink fieldCode="JN" term="%22100956087%22">Acta pharmacologica Sinica</searchLink> [Acta Pharmacol Sin] 2022 Mar; Vol. 43 (3), pp. 672-680. <i>Date of Electronic Publication: </i>2021 May 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100956087 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-7254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216714083%22">16714083 </searchLink><i>NLM ISO Abbreviation: </i>Acta Pharmacol Sin <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41401-021-00683-8
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              Text: 2022 Mar
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