Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
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| Title: | Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma. |
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| Authors: | Xiao L; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Somers K; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Murray J; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Pandher R; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Karsa M; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Ronca E; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Bongers A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Terry R; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Ehteda A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Gamble LD; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Issaeva N; Department of Otolaryngology/Head and Neck Surgery, Department of Pathology and Lab Medicine, Lineberger Comprehensive Cancer Center, UNC-Chapel Hill, Chapel Hill, North Carolina., Leonova KI; Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York., O'Connor A; Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia., Mayoh C; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Venkat P; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Quek H; Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Brand J; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Kusuma FK; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Pettitt JA; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Mosmann E; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Kearns A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Eden G; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Alfred S; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Allan S; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Zhai L; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia., Kamili A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Gifford AJ; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Carter DR; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.; School of Biomedical Engineering, University of Technology Sydney, Australia., Henderson MJ; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Fletcher JI; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia., Marshall G; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia., Johnstone RW; Immune Defence Laboratory, Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Cesare AJ; Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia., Ziegler DS; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia., Gudkov AV; Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York., Gurova KV; Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York., Norris MD; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia. mhaber@ccia.unsw.edu.au mnorris@ccia.unsw.edu.au.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.; University of New South Wales Centre for Childhood Cancer Research, Sydney, Australia., Haber M; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia. mhaber@ccia.unsw.edu.au mnorris@ccia.unsw.edu.au.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia. |
| Source: | Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Aug 01; Vol. 27 (15), pp. 4338-4352. Date of Electronic Publication: 2021 May 16. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 33994371 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Xiao+L%22">Xiao L</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Somers+K%22">Somers K</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Murray+J%22">Murray J</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Pandher+R%22">Pandher R</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Karsa+M%22">Karsa M</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Ronca+E%22">Ronca E</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Bongers+A%22">Bongers A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Terry+R%22">Terry R</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Ehteda+A%22">Ehteda A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Gamble+LD%22">Gamble LD</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Issaeva+N%22">Issaeva N</searchLink>; Department of Otolaryngology/Head and Neck Surgery, Department of Pathology and Lab Medicine, Lineberger Comprehensive Cancer Center, UNC-Chapel Hill, Chapel Hill, North Carolina.<br /><searchLink fieldCode="AU" term="%22Leonova+KI%22">Leonova KI</searchLink>; Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York.<br /><searchLink fieldCode="AU" term="%22O'Connor+A%22">O'Connor A</searchLink>; Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Mayoh+C%22">Mayoh C</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Venkat+P%22">Venkat P</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Quek+H%22">Quek H</searchLink>; Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Brand+J%22">Brand J</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Kusuma+FK%22">Kusuma FK</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Pettitt+JA%22">Pettitt JA</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Mosmann+E%22">Mosmann E</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Kearns+A%22">Kearns A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Eden+G%22">Eden G</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Alfred+S%22">Alfred S</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Allan+S%22">Allan S</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Zhai+L%22">Zhai L</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Kamili+A%22">Kamili A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Gifford+AJ%22">Gifford AJ</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Carter+DR%22">Carter DR</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.; School of Biomedical Engineering, University of Technology Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Henderson+MJ%22">Henderson MJ</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Fletcher+JI%22">Fletcher JI</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Marshall+G%22">Marshall G</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Johnstone+RW%22">Johnstone RW</searchLink>; Immune Defence Laboratory, Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Cesare+AJ%22">Cesare AJ</searchLink>; Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Ziegler+DS%22">Ziegler DS</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Gudkov+AV%22">Gudkov AV</searchLink>; Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York.<br /><searchLink fieldCode="AU" term="%22Gurova+KV%22">Gurova KV</searchLink>; Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York.<br /><searchLink fieldCode="AU" term="%22Norris+MD%22">Norris MD</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia. mhaber@ccia.unsw.edu.au mnorris@ccia.unsw.edu.au.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia.; University of New South Wales Centre for Childhood Cancer Research, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Haber+M%22">Haber M</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia. mhaber@ccia.unsw.edu.au mnorris@ccia.unsw.edu.au.; School of Women's and Children's Health, University of New South Wales Sydney, Randwick, New South Wales, Australia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2021 Aug 01; Vol. 27 (15), pp. 4338-4352. <i>Date of Electronic Publication: </i>2021 May 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=33994371 |
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