GATA zinc finger domain-containing protein 2A (GATAD2A) deficiency reactivates fetal haemoglobin in patients with β-thalassaemia through impaired formation of methyl-binding domain protein 2 (MBD2)-containing nucleosome remodelling and deacetylation (NuRD) complex.
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| Title: | GATA zinc finger domain-containing protein 2A (GATAD2A) deficiency reactivates fetal haemoglobin in patients with β-thalassaemia through impaired formation of methyl-binding domain protein 2 (MBD2)-containing nucleosome remodelling and deacetylation (NuRD) complex. |
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| Authors: | Liang Y; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China., Zhang X; Department of Hematology, 923rd Hospital of the People's Liberation Army, Nanning, Guangxi, China., Liu Y; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China., Wang L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, China., Ye Y; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China., Tan X; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China., Pu J; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China., Zhang Q; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China., Bao X; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China., Wei X; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China., Li D; Department of Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, Guangdong, China., Kurita R; Department of Research and Development, Central Blood Institute, Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan., Nakamura Y; Cell Engineering Division, RIKEN Bioresource Center, Tsukuba, Ibaraki, Japan., Li D; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, China., Xu X; Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Molecular Diagnostics of Human Genetic Diseases, Guangzhou, Guangdong, China.; Guangdong Engineering and Technology Research Center for Genetic Testing, Guangzhou, Guangdong, China. |
| Source: | British journal of haematology [Br J Haematol] 2021 Jun; Vol. 193 (6), pp. 1220-1227. Date of Electronic Publication: 2021 May 17. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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