Low doses of methylnaltrexone inhibits head and neck squamous cell carcinoma growth in vitro and in vivo by acting on the mu-opioid receptor.

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Title: Low doses of methylnaltrexone inhibits head and neck squamous cell carcinoma growth in vitro and in vivo by acting on the mu-opioid receptor.
Authors: Gorur A; Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Anesthesiology and Surgical Oncology Research Group, Houston, Texas, USA., Patiño M; Department of Anesthesiology, Massachusetts General Hospital, Harvard University, Boston, Massachusetts, USA., Shi T; Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Anesthesiology and Surgical Oncology Research Group, Houston, Texas, USA., Corrales G; Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Takahashi H; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Rangel R; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Gleber-Netto FO; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Pickering C; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Myers JN; Anesthesiology and Surgical Oncology Research Group, Houston, Texas, USA.; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Cata JP; Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Anesthesiology and Surgical Oncology Research Group, Houston, Texas, USA.
Source: Journal of cellular physiology [J Cell Physiol] 2021 Nov; Vol. 236 (11), pp. 7698-7710. Date of Electronic Publication: 2021 May 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4652 (Electronic) Linking ISSN: 00219541 NLM ISO Abbreviation: J Cell Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4652
DOI:10.1002/jcp.30421