Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer.

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Title: Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer.
Authors: Pereira B; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Chen CT; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Goyal L; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Walmsley C; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Pinto CJ; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Baiev I; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Allen R; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Henderson L; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Saha S; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Reyes S; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Taylor MS; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Fitzgerald DM; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Broudo MW; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Sahu A; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Gao X; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Winckler W; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Brannon AR; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Engelman JA; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Leary R; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Stone JR; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Campbell CD; Novartis Institutes for Biomedical Research, Cambridge, MA, USA. Katie.Campbell@novartis.com., Juric D; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA. Juric.Dejan@mgh.harvard.edu.
Source: Nature communications [Nat Commun] 2021 May 27; Vol. 12 (1), pp. 3199. Date of Electronic Publication: 2021 May 27.
Publication Type: Evaluation Study; Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-021-23394-4