A novel method of screening combinations of angiostatics identifies bevacizumab and temsirolimus as synergistic inhibitors of glioma-induced angiogenesis.
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| Title: | A novel method of screening combinations of angiostatics identifies bevacizumab and temsirolimus as synergistic inhibitors of glioma-induced angiogenesis. |
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| Authors: | Dorrell MI; Department of Biology, Point Loma Nazarene University, San Diego, CA, United States of America., Kast-Woelbern HR; Department of Biology, Point Loma Nazarene University, San Diego, CA, United States of America., Botts RT; Department of Mathematical, Information, and Computer Sciences, Point Loma Nazarene University, San Diego, CA, United States of America., Bravo SA; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Tremblay JR; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Giles S; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Wada JF; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Alexander M; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Garcia E; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Villegas G; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Booth CB; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Purington KJ; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Everett HM; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Siles EN; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Wheelock M; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Silva JA; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Fortin BM; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Lowey CA; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Hale AL; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Kurz TL; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Rusing JC; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Goral DM; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Thompson P; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Johnson AM; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Elson DJ; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Tadros R; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Gillette CE; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Coopwood C; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Rausch AL; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Snowbarger JM; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America. |
| Source: | PloS one [PLoS One] 2021 Jun 02; Vol. 16 (6), pp. e0252233. Date of Electronic Publication: 2021 Jun 02 (Print Publication: 2021). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34077449 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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