View in EDS

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.

Saved in:
Bibliographic Details
Title: NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
Authors: Flanagan DJ; Cancer Research UK Beatson Institute, Glasgow, UK., Pentinmikko N; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Luopajärvi K; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Willis NJ; Alzheimer's Research UK UCL Drug Discovery Institute, University College London, London, UK., Gilroy K; Cancer Research UK Beatson Institute, Glasgow, UK.; SpecifiCancer CRUK Grand Challenge Team (C7932/A29055), Department of Genetics, Harvard Medical School, Boston, MA, USA., Raven AP; Cancer Research UK Beatson Institute, Glasgow, UK.; SpecifiCancer CRUK Grand Challenge Team (C7932/A29055), Department of Genetics, Harvard Medical School, Boston, MA, USA., Mcgarry L; Cancer Research UK Beatson Institute, Glasgow, UK., Englund JI; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Webb AT; Department of Cell and Molecular Biology (CMB), Karolinska Institutet, Stockholm, Sweden., Scharaw S; Department of Cell and Molecular Biology (CMB), Karolinska Institutet, Stockholm, Sweden., Nasreddin N; Intestinal Stem Cell Biology Lab, Wellcome Trust Centre Human Genetics, University of Oxford, Oxford, UK., Hodder MC; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Ridgway RA; Cancer Research UK Beatson Institute, Glasgow, UK., Minnee E; Cancer Research UK Beatson Institute, Glasgow, UK.; Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Sphyris N; Cancer Research UK Beatson Institute, Glasgow, UK., Gilchrist E; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Najumudeen AK; Cancer Research UK Beatson Institute, Glasgow, UK., Romagnolo B; Université de Paris, Institut Cochin, INSERM, CNRS, Paris, France., Perret C; Université de Paris, Institut Cochin, INSERM, CNRS, Paris, France., Williams AC; Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK., Clevers H; SpecifiCancer CRUK Grand Challenge Team (C7932/A29055), Department of Genetics, Harvard Medical School, Boston, MA, USA.; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands., Nummela P; Department of Pathology, Applied Tumor Genomics, Research Programs Unit and HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Lähde M; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Wihuri Research Institute, University of Helsinki, Helsinki, Finland., Alitalo K; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Wihuri Research Institute, University of Helsinki, Helsinki, Finland., Hietakangas V; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Hedley A; Cancer Research UK Beatson Institute, Glasgow, UK., Clark W; Cancer Research UK Beatson Institute, Glasgow, UK., Nixon C; Cancer Research UK Beatson Institute, Glasgow, UK., Kirschner K; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Jones EY; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Ristimäki A; Department of Pathology, Applied Tumor Genomics, Research Programs Unit and HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Leedham SJ; Intestinal Stem Cell Biology Lab, Wellcome Trust Centre Human Genetics, University of Oxford, Oxford, UK., Fish PV; Alzheimer's Research UK UCL Drug Discovery Institute, University College London, London, UK.; The Francis Crick Institute, London, UK., Vincent JP; The Francis Crick Institute, London, UK., Katajisto P; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland. pekka.katajisto@helsinki.fi.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland. pekka.katajisto@helsinki.fi.; Department of Cell and Molecular Biology (CMB), Karolinska Institutet, Stockholm, Sweden. pekka.katajisto@helsinki.fi., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, UK. o.sansom@beatson.gla.ac.uk.; SpecifiCancer CRUK Grand Challenge Team (C7932/A29055), Department of Genetics, Harvard Medical School, Boston, MA, USA. o.sansom@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. o.sansom@beatson.gla.ac.uk.
Source: Nature [Nature] 2021 Jun; Vol. 594 (7863), pp. 430-435. Date of Electronic Publication: 2021 Jun 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 34079124
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Flanagan+DJ%22">Flanagan DJ</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Pentinmikko+N%22">Pentinmikko N</searchLink>; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Luopajärvi+K%22">Luopajärvi K</searchLink>; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Willis+NJ%22">Willis NJ</searchLink>; Alzheimer's Research UK UCL Drug Discovery Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gilroy+K%22">Gilroy K</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.; SpecifiCancer CRUK Grand Challenge Team (C7932/A29055), Department of Genetics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Raven+AP%22">Raven AP</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.; SpecifiCancer CRUK Grand Challenge Team (C7932/A29055), Department of Genetics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mcgarry+L%22">Mcgarry L</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Englund+JI%22">Englund JI</searchLink>; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Webb+AT%22">Webb AT</searchLink>; Department of Cell and Molecular Biology (CMB), Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Scharaw+S%22">Scharaw S</searchLink>; Department of Cell and Molecular Biology (CMB), Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Nasreddin+N%22">Nasreddin N</searchLink>; Intestinal Stem Cell Biology Lab, Wellcome Trust Centre Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hodder+MC%22">Hodder MC</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Ridgway+RA%22">Ridgway RA</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Minnee+E%22">Minnee E</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.; Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sphyris+N%22">Sphyris N</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Gilchrist+E%22">Gilchrist E</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Najumudeen+AK%22">Najumudeen AK</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Romagnolo+B%22">Romagnolo B</searchLink>; Université de Paris, Institut Cochin, INSERM, CNRS, Paris, France.<br /><searchLink fieldCode="AU" term="%22Perret+C%22">Perret C</searchLink>; Université de Paris, Institut Cochin, INSERM, CNRS, Paris, France.<br /><searchLink fieldCode="AU" term="%22Williams+AC%22">Williams AC</searchLink>; Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Clevers+H%22">Clevers H</searchLink>; SpecifiCancer CRUK Grand Challenge Team (C7932/A29055), Department of Genetics, Harvard Medical School, Boston, MA, USA.; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nummela+P%22">Nummela P</searchLink>; Department of Pathology, Applied Tumor Genomics, Research Programs Unit and HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Lähde+M%22">Lähde M</searchLink>; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Wihuri Research Institute, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Alitalo+K%22">Alitalo K</searchLink>; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Wihuri Research Institute, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hietakangas+V%22">Hietakangas V</searchLink>; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hedley+A%22">Hedley A</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Clark+W%22">Clark W</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Nixon+C%22">Nixon C</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Kirschner+K%22">Kirschner K</searchLink>; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Jones+EY%22">Jones EY</searchLink>; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ristimäki+A%22">Ristimäki A</searchLink>; Department of Pathology, Applied Tumor Genomics, Research Programs Unit and HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Leedham+SJ%22">Leedham SJ</searchLink>; Intestinal Stem Cell Biology Lab, Wellcome Trust Centre Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Fish+PV%22">Fish PV</searchLink>; Alzheimer's Research UK UCL Drug Discovery Institute, University College London, London, UK.; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Vincent+JP%22">Vincent JP</searchLink>; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Katajisto+P%22">Katajisto P</searchLink>; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland. pekka.katajisto@helsinki.fi.; Molecular and Integrative Bioscience Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland. pekka.katajisto@helsinki.fi.; Department of Cell and Molecular Biology (CMB), Karolinska Institutet, Stockholm, Sweden. pekka.katajisto@helsinki.fi.<br /><searchLink fieldCode="AU" term="%22Sansom+OJ%22">Sansom OJ</searchLink>; Cancer Research UK Beatson Institute, Glasgow, UK. o.sansom@beatson.gla.ac.uk.; SpecifiCancer CRUK Grand Challenge Team (C7932/A29055), Department of Genetics, Harvard Medical School, Boston, MA, USA. o.sansom@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. o.sansom@beatson.gla.ac.uk.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2021 Jun; Vol. 594 (7863), pp. 430-435. <i>Date of Electronic Publication: </i>2021 Jun 02.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34079124
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41586-021-03525-z
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 430
    Titles:
      – TitleFull: NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Flanagan DJ
      – PersonEntity:
          Name:
            NameFull: Pentinmikko N
      – PersonEntity:
          Name:
            NameFull: Luopajärvi K
      – PersonEntity:
          Name:
            NameFull: Willis NJ
      – PersonEntity:
          Name:
            NameFull: Gilroy K
      – PersonEntity:
          Name:
            NameFull: Raven AP
      – PersonEntity:
          Name:
            NameFull: Mcgarry L
      – PersonEntity:
          Name:
            NameFull: Englund JI
      – PersonEntity:
          Name:
            NameFull: Webb AT
      – PersonEntity:
          Name:
            NameFull: Scharaw S
      – PersonEntity:
          Name:
            NameFull: Nasreddin N
      – PersonEntity:
          Name:
            NameFull: Hodder MC
      – PersonEntity:
          Name:
            NameFull: Ridgway RA
      – PersonEntity:
          Name:
            NameFull: Minnee E
      – PersonEntity:
          Name:
            NameFull: Sphyris N
      – PersonEntity:
          Name:
            NameFull: Gilchrist E
      – PersonEntity:
          Name:
            NameFull: Najumudeen AK
      – PersonEntity:
          Name:
            NameFull: Romagnolo B
      – PersonEntity:
          Name:
            NameFull: Perret C
      – PersonEntity:
          Name:
            NameFull: Williams AC
      – PersonEntity:
          Name:
            NameFull: Clevers H
      – PersonEntity:
          Name:
            NameFull: Nummela P
      – PersonEntity:
          Name:
            NameFull: Lähde M
      – PersonEntity:
          Name:
            NameFull: Alitalo K
      – PersonEntity:
          Name:
            NameFull: Hietakangas V
      – PersonEntity:
          Name:
            NameFull: Hedley A
      – PersonEntity:
          Name:
            NameFull: Clark W
      – PersonEntity:
          Name:
            NameFull: Nixon C
      – PersonEntity:
          Name:
            NameFull: Kirschner K
      – PersonEntity:
          Name:
            NameFull: Jones EY
      – PersonEntity:
          Name:
            NameFull: Ristimäki A
      – PersonEntity:
          Name:
            NameFull: Leedham SJ
      – PersonEntity:
          Name:
            NameFull: Fish PV
      – PersonEntity:
          Name:
            NameFull: Vincent JP
      – PersonEntity:
          Name:
            NameFull: Katajisto P
      – PersonEntity:
          Name:
            NameFull: Sansom OJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: 2021 Jun
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1476-4687
          Numbering:
            – Type: volume
              Value: 594
            – Type: issue
              Value: 7863
          Titles:
            – TitleFull: Nature
              Type: main
ResultId 1