Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction.
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| Title: | Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction. |
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| Authors: | Lopez-Rodriguez AB; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Hennessy E; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Murray CL; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Nazmi A; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Delaney HJ; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.; Discipline of Physiology, School of Medicine, Trinity College Dublin, Dublin, Rep. of Ireland., Healy D; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Fagan SG; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Rooney M; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Stewart E; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Lewis A; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., de Barra N; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Scarry P; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Riggs-Miller L; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland., Boche D; Clinical Neurosciences, Clinical and Experimental Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK., Cunningham MO; Discipline of Physiology, School of Medicine, Trinity College Dublin, Dublin, Rep. of Ireland., Cunningham C; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland. |
| Source: | Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2021 Oct; Vol. 17 (10), pp. 1735-1755. Date of Electronic Publication: 2021 Jun 03. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34080771 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lopez-Rodriguez+AB%22">Lopez-Rodriguez AB</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Hennessy+E%22">Hennessy E</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Murray+CL%22">Murray CL</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Nazmi+A%22">Nazmi A</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Delaney+HJ%22">Delaney HJ</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.; Discipline of Physiology, School of Medicine, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Healy+D%22">Healy D</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Fagan+SG%22">Fagan SG</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Rooney+M%22">Rooney M</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Stewart+E%22">Stewart E</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Lewis+A%22">Lewis A</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22de+Barra+N%22">de Barra N</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Scarry+P%22">Scarry P</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Riggs-Miller+L%22">Riggs-Miller L</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Boche+D%22">Boche D</searchLink>; Clinical Neurosciences, Clinical and Experimental Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Cunningham+MO%22">Cunningham MO</searchLink>; Discipline of Physiology, School of Medicine, Trinity College Dublin, Dublin, Rep. of Ireland.<br /><searchLink fieldCode="AU" term="%22Cunningham+C%22">Cunningham C</searchLink>; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Rep. of Ireland. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2021 Oct; Vol. 17 (10), pp. 1735-1755. <i>Date of Electronic Publication: </i>2021 Jun 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34080771 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/alz.12341 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1735 Titles: – TitleFull: Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lopez-Rodriguez AB – PersonEntity: Name: NameFull: Hennessy E – PersonEntity: Name: NameFull: Murray CL – PersonEntity: Name: NameFull: Nazmi A – PersonEntity: Name: NameFull: Delaney HJ – PersonEntity: Name: NameFull: Healy D – PersonEntity: Name: NameFull: Fagan SG – PersonEntity: Name: NameFull: Rooney M – PersonEntity: Name: NameFull: Stewart E – PersonEntity: Name: NameFull: Lewis A – PersonEntity: Name: NameFull: de Barra N – PersonEntity: Name: NameFull: Scarry P – PersonEntity: Name: NameFull: Riggs-Miller L – PersonEntity: Name: NameFull: Boche D – PersonEntity: Name: NameFull: Cunningham MO – PersonEntity: Name: NameFull: Cunningham C IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2021 Oct Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1552-5279 Numbering: – Type: volume Value: 17 – Type: issue Value: 10 Titles: – TitleFull: Alzheimer's & dementia : the journal of the Alzheimer's Association Type: main |
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