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Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma.

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Title: Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma.
Authors: Simonds EF; Department of Neurology, University of California San Francisco, San Francisco, California, USA., Lu ED; Department of Neurology, University of California San Francisco, San Francisco, California, USA., Badillo O; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Karimi S; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Liu EV; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA., Tamaki W; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA., Rancan C; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA., Downey KM; Department of Neurology, University of California San Francisco, San Francisco, California, USA., Stultz J; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA., Sinha M; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA., McHenry LK; Department of Neurology, University of California San Francisco, San Francisco, California, USA., Nasholm NM; Department of Neurology, University of California San Francisco, San Francisco, California, USA., Chuntova P; Department of Neurological Surgery, University of California San Francisco, San Francisco, California, USA., Sundström A; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Genoud V; Translational Research Centre in Oncohaematology, Department of Medicine, University of Geneva, Geneva, Switzerland., Shahani SA; Department of Pediatrics, City of Hope National Medical Center, Duarte, California, USA., Wang LD; Department of Pediatrics, City of Hope National Medical Center, Duarte, California, USA.; Department of Immuno-Oncology, City of Hope National Medical Center, Duarte, California, USA., Brown CE; Departments of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte CA, Duarte, California, USA., Walker PR; Translational Research Centre in Oncohaematology, Department of Medicine, University of Geneva, Geneva, Switzerland., Swartling FJ; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Fong L; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, California, USA., Okada H; Department of Neurological Surgery, University of California San Francisco, San Francisco, California, USA hideho.okada@ucsf.edu waweiss@gmail.com mats.hellstrom@igp.uu.se.; Parker Institute for Cancer Immunotherapy, San Francisco, California, USA., Weiss WA; Parker Institute for Cancer Immunotherapy, San Francisco, California, USA hideho.okada@ucsf.edu waweiss@gmail.com mats.hellstrom@igp.uu.se.; Departments of Neurology, Neurological Surgery, and Pediatrics, University of California San Francisco, San Francisco, California, USA.; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA., Hellström M; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden hideho.okada@ucsf.edu waweiss@gmail.com mats.hellstrom@igp.uu.se.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 Jun; Vol. 9 (6).
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Simonds+EF%22">Simonds EF</searchLink>; Department of Neurology, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Lu+ED%22">Lu ED</searchLink>; Department of Neurology, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Badillo+O%22">Badillo O</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Karimi+S%22">Karimi S</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Liu+EV%22">Liu EV</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Tamaki+W%22">Tamaki W</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Rancan+C%22">Rancan C</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Downey+KM%22">Downey KM</searchLink>; Department of Neurology, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Stultz+J%22">Stultz J</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Sinha+M%22">Sinha M</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22McHenry+LK%22">McHenry LK</searchLink>; Department of Neurology, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Nasholm+NM%22">Nasholm NM</searchLink>; Department of Neurology, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Chuntova+P%22">Chuntova P</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Sundström+A%22">Sundström A</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Genoud+V%22">Genoud V</searchLink>; Translational Research Centre in Oncohaematology, Department of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Shahani+SA%22">Shahani SA</searchLink>; Department of Pediatrics, City of Hope National Medical Center, Duarte, California, USA.<br /><searchLink fieldCode="AU" term="%22Wang+LD%22">Wang LD</searchLink>; Department of Pediatrics, City of Hope National Medical Center, Duarte, California, USA.; Department of Immuno-Oncology, City of Hope National Medical Center, Duarte, California, USA.<br /><searchLink fieldCode="AU" term="%22Brown+CE%22">Brown CE</searchLink>; Departments of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte CA, Duarte, California, USA.<br /><searchLink fieldCode="AU" term="%22Walker+PR%22">Walker PR</searchLink>; Translational Research Centre in Oncohaematology, Department of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Swartling+FJ%22">Swartling FJ</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Fong+L%22">Fong L</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Okada+H%22">Okada H</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, California, USA hideho.okada@ucsf.edu waweiss@gmail.com mats.hellstrom@igp.uu.se.; Parker Institute for Cancer Immunotherapy, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Weiss+WA%22">Weiss WA</searchLink>; Parker Institute for Cancer Immunotherapy, San Francisco, California, USA hideho.okada@ucsf.edu waweiss@gmail.com mats.hellstrom@igp.uu.se.; Departments of Neurology, Neurological Surgery, and Pediatrics, University of California San Francisco, San Francisco, California, USA.; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Hellström+M%22">Hellström M</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden hideho.okada@ucsf.edu waweiss@gmail.com mats.hellstrom@igp.uu.se.
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        Value: 10.1136/jitc-2020-002181
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              Text: 2021 Jun
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