Efficacy of RyR2 inhibitor EL20 in induced pluripotent stem cell-derived cardiomyocytes from a patient with catecholaminergic polymorphic ventricular tachycardia.

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Title: Efficacy of RyR2 inhibitor EL20 in induced pluripotent stem cell-derived cardiomyocytes from a patient with catecholaminergic polymorphic ventricular tachycardia.
Authors: Word TA; Department of Molecular Physiology & Biophysics, Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX, USA., Quick AP; Section of Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Miyake CY; Department of Molecular Physiology & Biophysics, Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX, USA.; Section of Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Shak MK; Department of Molecular Physiology & Biophysics, Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX, USA., Pan X; Department of Molecular Physiology & Biophysics, Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX, USA., Kim JJ; Department of Molecular & Cellular Biology, Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA., Allen HD; Department of Molecular & Cellular Biology, Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA., Sibrian-Vazquez M; Elex Biotech Inc, Portland, OR, USA., Strongin RM; Department of Chemistry, Portland State University, Portland, OR, USA., Landstrom AP; Department of Pediatrics, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA.; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Wehrens XHT; Department of Molecular Physiology & Biophysics, Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX, USA.; Section of Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.; Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, TX, USA.; Department of Neuroscience, Section of Cardiology, Baylor College of Medicine, Houston, TX, USA.; Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA.
Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2021 Jun 10. Date of Electronic Publication: 2021 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1582-4934
DOI:10.1111/jcmm.16521