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The structural basis of fatty acid elongation by the ELOVL elongases.

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Title: The structural basis of fatty acid elongation by the ELOVL elongases.
Authors: Nie L; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; CRELUX GmbH, Planegg-Martinsried, Germany., Pascoa TC; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Pike ACW; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Bushell SR; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Orbit Discovery, Oxford, UK., Quigley A; Membrane Protein Laboratory, Diamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot, UK.; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, UK., Ruda GF; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Evotec Ltd, Milton, Abingdon, UK., Chu A; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Department of Biochemistry, Oxford University, Oxford, UK., Cole V; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Genomics Centre, South African Medical Research Council, Cape Town, South Africa., Speedman D; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Moreira T; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Shrestha L; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Mukhopadhyay SMM; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Burgess-Brown NA; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Love JD; Albert Einstein College of Medicine, Department of Biochemistry, Bronx, NY, USA.; Novo Nordisk A/S, Måløv, Denmark., Brennan PE; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Alzheimer's Research UK Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Carpenter EP; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK. liz.carpenter@cmd.ox.ac.uk.; Vertex Pharmaceuticals Ltd, Milton, Abingdon, UK. liz.carpenter@cmd.ox.ac.uk.
Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2021 Jun; Vol. 28 (6), pp. 512-520. Date of Electronic Publication: 2021 Jun 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE
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  Data: The structural basis of fatty acid elongation by the ELOVL elongases.
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  Data: <searchLink fieldCode="AU" term="%22Nie+L%22">Nie L</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; CRELUX GmbH, Planegg-Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Pascoa+TC%22">Pascoa TC</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Pike+ACW%22">Pike ACW</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Bushell+SR%22">Bushell SR</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Orbit Discovery, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Quigley+A%22">Quigley A</searchLink>; Membrane Protein Laboratory, Diamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot, UK.; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, UK.<br /><searchLink fieldCode="AU" term="%22Ruda+GF%22">Ruda GF</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Evotec Ltd, Milton, Abingdon, UK.<br /><searchLink fieldCode="AU" term="%22Chu+A%22">Chu A</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Department of Biochemistry, Oxford University, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cole+V%22">Cole V</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Genomics Centre, South African Medical Research Council, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Speedman+D%22">Speedman D</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Moreira+T%22">Moreira T</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Shrestha+L%22">Shrestha L</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mukhopadhyay+SMM%22">Mukhopadhyay SMM</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Burgess-Brown+NA%22">Burgess-Brown NA</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Love+JD%22">Love JD</searchLink>; Albert Einstein College of Medicine, Department of Biochemistry, Bronx, NY, USA.; Novo Nordisk A/S, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Brennan+PE%22">Brennan PE</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Alzheimer's Research UK Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Carpenter+EP%22">Carpenter EP</searchLink>; Structural Genomics Consortium, Centre for Medicines Discovery, University of Oxford, Oxford, UK. liz.carpenter@cmd.ox.ac.uk.; Vertex Pharmaceuticals Ltd, Milton, Abingdon, UK. liz.carpenter@cmd.ox.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101186374%22">Nature structural & molecular biology</searchLink> [Nat Struct Mol Biol] 2021 Jun; Vol. 28 (6), pp. 512-520. <i>Date of Electronic Publication: </i>2021 Jun 10.
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