DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.

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Title: DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Authors: Homma H; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Tanaka H; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Jin M; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Jin X; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Huang Y; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Yoshioka Y; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Bertens CJ; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.; Department of Biomolecular Science, Faculty of Science, Toho University, Chiba, Japan.; School for Mental Health and Neuroscience (MHeNs), University Eye Clinic Maastricht, Maastricht University, Maastricht, The Netherlands., Tsumaki K; Department of Biomolecular Science, Faculty of Science, Toho University, Chiba, Japan., Kondo K; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Shiwaku H; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.; Department of Psychiatry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Tagawa K; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Akatsu H; Department of Community-Based Medical Education, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Atsuta N; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Furukawa K; Division of Community Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan., Ishiki A; Department of Geriatrics and Gerontology, Division of Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan., Waragai M; Department of Neurology, Higashi Matsudo Municipal Hospital, Chiba, Japan., Ohtomo G; Department of Neurology, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan., Iwata A; Department of Neurology, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan., Yokota T; Department of Neurology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Inoue H; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.; Drug-Discovery Cellular Basis Development Team, RIKEN BioResource Center, Kyoto, Japan., Arai H; Department of Geriatrics and Gerontology, Division of Brain Science, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan., Sobue G; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Sone M; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.; Department of Biomolecular Science, Faculty of Science, Toho University, Chiba, Japan., Fujita K; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Okazawa H; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan okazawa-tky@umin.ac.jp.; Center for Brain Integration Research, Tokyo Medical and Dental University, Tokyo, Japan.
Source: Life science alliance [Life Sci Alliance] 2021 Jun 15; Vol. 4 (7). Date of Electronic Publication: 2021 Jun 15 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2575-1077
DOI:10.26508/lsa.202101022