Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs.

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Title: Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs.
Authors: Senyuk V; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA., Eskandari N; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA., Jiang Y; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA; Departments of Anesthesiology and Pharmacology and Regenerative Medicine, University of Illinois, Chicago, IL, USA., Garcia-Varela R; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA; Tecnologico de Monterrey, Centro de Biotecnologia-FEMSA, Escuela de Ingenieria y Ciencias, Monterrey N.L., Mexico., Sundstrom R; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA., Leanza L; Department of Biology, University of Padova, Padova, Italy., Peruzzo R; Department of Biology, University of Padova, Padova, Italy., Burkard M; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA., Minshall RD; Departments of Anesthesiology and Pharmacology and Regenerative Medicine, University of Illinois, Chicago, IL, USA., Gentile S; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA. Electronic address: sgentile@uic.edu.
Source: Redox biology [Redox Biol] 2021 Sep; Vol. 45, pp. 102030. Date of Electronic Publication: 2021 Jun 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs.
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  Data: <searchLink fieldCode="AU" term="%22Senyuk+V%22">Senyuk V</searchLink>; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Eskandari+N%22">Eskandari N</searchLink>; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA; Departments of Anesthesiology and Pharmacology and Regenerative Medicine, University of Illinois, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Garcia-Varela+R%22">Garcia-Varela R</searchLink>; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA; Tecnologico de Monterrey, Centro de Biotecnologia-FEMSA, Escuela de Ingenieria y Ciencias, Monterrey N.L., Mexico.<br /><searchLink fieldCode="AU" term="%22Sundstrom+R%22">Sundstrom R</searchLink>; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Leanza+L%22">Leanza L</searchLink>; Department of Biology, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Peruzzo+R%22">Peruzzo R</searchLink>; Department of Biology, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Burkard+M%22">Burkard M</searchLink>; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Minshall+RD%22">Minshall RD</searchLink>; Departments of Anesthesiology and Pharmacology and Regenerative Medicine, University of Illinois, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Gentile+S%22">Gentile S</searchLink>; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA. Electronic address: sgentile@uic.edu.
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  Data: <searchLink fieldCode="JN" term="%22101605639%22">Redox biology</searchLink> [Redox Biol] 2021 Sep; Vol. 45, pp. 102030. <i>Date of Electronic Publication: </i>2021 Jun 12.
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