Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.

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Title: Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.
Authors: Vennekens A; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Laporte E; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Hermans F; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.; Laboratory of Morphology, Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, Belgium., Cox B; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Modave E; Center for Cancer Biology, Vlaams Instituut voor Biotechnologie, 3000 Leuven, Belgium.; Laboratory for Intestinal Neuroimmune Interactions, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Janiszewski A; Laboratory for Cellular Reprogramming and Epigenetic Regulation, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Nys C; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Kobayashi H; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.; Department of Anatomy and Structural Science, Yamagata University Faculty of Medicine, Yamagata 990-9585, Japan., Malengier-Devlies B; Immunity and Inflammation Research Group, Department of Microbiology, Immunology and Transplantation, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Chappell J; Laboratory for Cellular Reprogramming and Epigenetic Regulation, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Matthys P; Immunity and Inflammation Research Group, Department of Microbiology, Immunology and Transplantation, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Garcia MI; Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Faculty of Medicine, Université Libre de Bruxelles, 1070 Bruxelles, Belgium., Pasque V; Laboratory for Cellular Reprogramming and Epigenetic Regulation, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Lambrechts D; Center for Cancer Biology, Vlaams Instituut voor Biotechnologie, 3000 Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Vankelecom H; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium; hugo.v@kuleuven.be.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jun 22; Vol. 118 (25).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland.
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  Data: <searchLink fieldCode="AU" term="%22Vennekens+A%22">Vennekens A</searchLink>; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Laporte+E%22">Laporte E</searchLink>; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Hermans+F%22">Hermans F</searchLink>; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.; Laboratory of Morphology, Biomedical Research Institute, Hasselt University, 3590 Diepenbeek, Belgium.<br /><searchLink fieldCode="AU" term="%22Cox+B%22">Cox B</searchLink>; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Modave+E%22">Modave E</searchLink>; Center for Cancer Biology, Vlaams Instituut voor Biotechnologie, 3000 Leuven, Belgium.; Laboratory for Intestinal Neuroimmune Interactions, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Janiszewski+A%22">Janiszewski A</searchLink>; Laboratory for Cellular Reprogramming and Epigenetic Regulation, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Nys+C%22">Nys C</searchLink>; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Kobayashi+H%22">Kobayashi H</searchLink>; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.; Department of Anatomy and Structural Science, Yamagata University Faculty of Medicine, Yamagata 990-9585, Japan.<br /><searchLink fieldCode="AU" term="%22Malengier-Devlies+B%22">Malengier-Devlies B</searchLink>; Immunity and Inflammation Research Group, Department of Microbiology, Immunology and Transplantation, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Chappell+J%22">Chappell J</searchLink>; Laboratory for Cellular Reprogramming and Epigenetic Regulation, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Matthys+P%22">Matthys P</searchLink>; Immunity and Inflammation Research Group, Department of Microbiology, Immunology and Transplantation, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Garcia+MI%22">Garcia MI</searchLink>; Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Faculty of Medicine, Université Libre de Bruxelles, 1070 Bruxelles, Belgium.<br /><searchLink fieldCode="AU" term="%22Pasque+V%22">Pasque V</searchLink>; Laboratory for Cellular Reprogramming and Epigenetic Regulation, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Lambrechts+D%22">Lambrechts D</searchLink>; Center for Cancer Biology, Vlaams Instituut voor Biotechnologie, 3000 Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vankelecom+H%22">Vankelecom H</searchLink>; Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, Leuven Stem Cell Institute, Katholieke Universiteit Leuven, 3000 Leuven, Belgium; hugo.v@kuleuven.be.
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