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Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors.

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Title: Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors.
Authors: Gupta R; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, 6900 Lake Nona Blvd., Orlando, Florida 32827, United States., Al-Kharji NMSA; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States., Alqurafi MA; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States., Nguyen TQ; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States., Chai W; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States., Quan P; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States., Malhotra R; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States., Simcox BS; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, 6900 Lake Nona Blvd., Orlando, Florida 32827, United States., Mortimer P; Department of Chemistry, Mass Spectrometry Facility, The Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States., Brammer Basta LA; Chemistry Department, United States Naval Academy, 572M Holloway Road, Annapolis, Maryland 21402, United States., Rohde KH; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, 6900 Lake Nona Blvd., Orlando, Florida 32827, United States., Buynak JD; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States.
Source: ACS infectious diseases [ACS Infect Dis] 2021 Aug 13; Vol. 7 (8), pp. 2425-2436. Date of Electronic Publication: 2021 Jun 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Gupta+R%22">Gupta R</searchLink>; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, 6900 Lake Nona Blvd., Orlando, Florida 32827, United States.<br /><searchLink fieldCode="AU" term="%22Al-Kharji+NMSA%22">Al-Kharji NMSA</searchLink>; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States.<br /><searchLink fieldCode="AU" term="%22Alqurafi+MA%22">Alqurafi MA</searchLink>; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States.<br /><searchLink fieldCode="AU" term="%22Nguyen+TQ%22">Nguyen TQ</searchLink>; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States.<br /><searchLink fieldCode="AU" term="%22Chai+W%22">Chai W</searchLink>; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States.<br /><searchLink fieldCode="AU" term="%22Quan+P%22">Quan P</searchLink>; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States.<br /><searchLink fieldCode="AU" term="%22Malhotra+R%22">Malhotra R</searchLink>; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States.<br /><searchLink fieldCode="AU" term="%22Simcox+BS%22">Simcox BS</searchLink>; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, 6900 Lake Nona Blvd., Orlando, Florida 32827, United States.<br /><searchLink fieldCode="AU" term="%22Mortimer+P%22">Mortimer P</searchLink>; Department of Chemistry, Mass Spectrometry Facility, The Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.<br /><searchLink fieldCode="AU" term="%22Brammer+Basta+LA%22">Brammer Basta LA</searchLink>; Chemistry Department, United States Naval Academy, 572M Holloway Road, Annapolis, Maryland 21402, United States.<br /><searchLink fieldCode="AU" term="%22Rohde+KH%22">Rohde KH</searchLink>; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, 6900 Lake Nona Blvd., Orlando, Florida 32827, United States.<br /><searchLink fieldCode="AU" term="%22Buynak+JD%22">Buynak JD</searchLink>; Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, United States.
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  Data: <searchLink fieldCode="JN" term="%22101654580%22">ACS infectious diseases</searchLink> [ACS Infect Dis] 2021 Aug 13; Vol. 7 (8), pp. 2425-2436. <i>Date of Electronic Publication: </i>2021 Jun 30.
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