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Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis.

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Title: Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis.
Authors: Scherlinger M; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Guillotin V; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.; Department of Internal Medicine, Saint André, Bordeaux University Hospital, 33076 Bordeaux, France., Douchet I; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Vacher P; INSERM U1218, 33076 Bordeaux, France., Boizard-Moracchini A; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Guegan JP; Explicyte, 229 Cours de l'Argonne, 33000 Bordeaux, France., Garreau A; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Merillon N; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Vermorel A; Nephrology Department, Bordeaux University Hospital, 33076 Bordeaux, France., Ribeiro E; Department of Internal Medicine, Saint André, Bordeaux University Hospital, 33076 Bordeaux, France., Machelart I; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, 33604, Pessac, France., Lazaro E; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, 33604, Pessac, France., Couzi L; Nephrology Department, Bordeaux University Hospital, 33076 Bordeaux, France., Duffau P; Department of Internal Medicine, Saint André, Bordeaux University Hospital, 33076 Bordeaux, France., Barnetche T; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France., Pellegrin JL; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, 33604, Pessac, France., Viallard JF; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, 33604, Pessac, France., Saleh M; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Schaeverbeke T; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France., Legembre P; Contrôle de la Réponse Immune B et lymphoproliférations, CRIBL, UMR CNRS 7276, INSERM 1262, Limoges, France., Truchetet ME; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Dumortier H; CNRS, UPR 3572 I2CT, IBMC, 67000 Strasbourg, France., Contin-Bordes C; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.; Department of Immunology and Immunogenetics, Bordeaux University Hospital, 33076 Bordeaux, France., Sisirak V; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Richez C; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France. patrick.blanco@chu-bordeaux.fr christophe.richez@chu-bordeaux.fr.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France., Blanco P; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France. patrick.blanco@chu-bordeaux.fr christophe.richez@chu-bordeaux.fr.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.; Department of Immunology and Immunogenetics, Bordeaux University Hospital, 33076 Bordeaux, France.
Source: Science translational medicine [Sci Transl Med] 2021 Jun 30; Vol. 13 (600).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Scherlinger+M%22">Scherlinger M</searchLink>; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Guillotin+V%22">Guillotin V</searchLink>; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.; Department of Internal Medicine, Saint André, Bordeaux University Hospital, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Douchet+I%22">Douchet I</searchLink>; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Vacher+P%22">Vacher P</searchLink>; INSERM U1218, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Boizard-Moracchini+A%22">Boizard-Moracchini A</searchLink>; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Guegan+JP%22">Guegan JP</searchLink>; Explicyte, 229 Cours de l'Argonne, 33000 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Garreau+A%22">Garreau A</searchLink>; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Merillon+N%22">Merillon N</searchLink>; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Vermorel+A%22">Vermorel A</searchLink>; Nephrology Department, Bordeaux University Hospital, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Ribeiro+E%22">Ribeiro E</searchLink>; Department of Internal Medicine, Saint André, Bordeaux University Hospital, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Machelart+I%22">Machelart I</searchLink>; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, 33604, Pessac, France.<br /><searchLink fieldCode="AU" term="%22Lazaro+E%22">Lazaro E</searchLink>; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, 33604, Pessac, France.<br /><searchLink fieldCode="AU" term="%22Couzi+L%22">Couzi L</searchLink>; Nephrology Department, Bordeaux University Hospital, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Duffau+P%22">Duffau P</searchLink>; Department of Internal Medicine, Saint André, Bordeaux University Hospital, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Barnetche+T%22">Barnetche T</searchLink>; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Pellegrin+JL%22">Pellegrin JL</searchLink>; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, 33604, Pessac, France.<br /><searchLink fieldCode="AU" term="%22Viallard+JF%22">Viallard JF</searchLink>; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; Department of Internal Medicine, Haut-Leveque, Bordeaux University Hospital, 33604, Pessac, France.<br /><searchLink fieldCode="AU" term="%22Saleh+M%22">Saleh M</searchLink>; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Schaeverbeke+T%22">Schaeverbeke T</searchLink>; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Legembre+P%22">Legembre P</searchLink>; Contrôle de la Réponse Immune B et lymphoproliférations, CRIBL, UMR CNRS 7276, INSERM 1262, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Truchetet+ME%22">Truchetet ME</searchLink>; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Dumortier+H%22">Dumortier H</searchLink>; CNRS, UPR 3572 I2CT, IBMC, 67000 Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Contin-Bordes+C%22">Contin-Bordes C</searchLink>; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.; Department of Immunology and Immunogenetics, Bordeaux University Hospital, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Sisirak+V%22">Sisirak V</searchLink>; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Richez+C%22">Richez C</searchLink>; Department of Rheumatology, Pellegrin, Bordeaux University Hospital, 33076 Bordeaux, France. patrick.blanco@chu-bordeaux.fr christophe.richez@chu-bordeaux.fr.; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Blanco+P%22">Blanco P</searchLink>; Centre national de référence maladie auto-immune et systémique rares Est/Sud-Ouest (RESO), Bordeaux University Hospital, 33076 Bordeaux, France. patrick.blanco@chu-bordeaux.fr christophe.richez@chu-bordeaux.fr.; UMR-CNRS 5164, ImmunoConcept, University of Bordeaux, 33076 Bordeaux, France.; Department of Immunology and Immunogenetics, Bordeaux University Hospital, 33076 Bordeaux, France.
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