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Methylprednisolone Pulses Plus Tacrolimus in Addition to Standard of Care vs. Standard of Care Alone in Patients With Severe COVID-19. A Randomized Controlled Trial.

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Title: Methylprednisolone Pulses Plus Tacrolimus in Addition to Standard of Care vs. Standard of Care Alone in Patients With Severe COVID-19. A Randomized Controlled Trial.
Authors: Solanich X; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Antolí A; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Rocamora-Blanch G; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Padullés N; Department of Pharmacy, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain., Fanlo-Maresma M; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Iriarte A; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Mitjavila F; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain., Capdevila O; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain., Riera-Mestre A; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain., Bas J; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.; Department of Immunology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Vicens-Zygmunt V; Department of Pneumology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Niubó J; Department of Microbiology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Calvo N; Department of Diagnostic Imaging, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Bolivar S; Department of Diagnostic Imaging, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Rigo-Bonnin R; Department of Clinical Laboratory, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Mensa-Vilaró A; Department of Immunology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain., Arregui L; HUB-ICO-IDIBELL Biobank, Spanish Clinical Research Network, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Tebe C; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.; Department of Biostatistics, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Videla S; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.; Department of Clinical Pharmacology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Clinical Research and Clinical Trial Unit (UICEC-IDIBELL), Spanish Clinical Research Network, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Hereu P; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.; Department of Clinical Pharmacology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Clinical Research and Clinical Trial Unit (UICEC-IDIBELL), Spanish Clinical Research Network, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Corbella X; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; School of Medicine, Universitat Internacional de Catalunya, Barcelona, Spain.
Source: Frontiers in medicine [Front Med (Lausanne)] 2021 Jun 14; Vol. 8, pp. 691712. Date of Electronic Publication: 2021 Jun 14 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Solanich+X%22">Solanich X</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Antolí+A%22">Antolí A</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rocamora-Blanch+G%22">Rocamora-Blanch G</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Padullés+N%22">Padullés N</searchLink>; Department of Pharmacy, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Fanlo-Maresma+M%22">Fanlo-Maresma M</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Iriarte+A%22">Iriarte A</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mitjavila+F%22">Mitjavila F</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Capdevila+O%22">Capdevila O</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Riera-Mestre+A%22">Riera-Mestre A</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bas+J%22">Bas J</searchLink>; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.; Department of Immunology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Vicens-Zygmunt+V%22">Vicens-Zygmunt V</searchLink>; Department of Pneumology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Niubó+J%22">Niubó J</searchLink>; Department of Microbiology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Calvo+N%22">Calvo N</searchLink>; 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Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.; Department of Biostatistics, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Videla+S%22">Videla S</searchLink>; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.; Department of Clinical Pharmacology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Clinical Research and Clinical Trial Unit (UICEC-IDIBELL), Spanish Clinical Research Network, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Hereu+P%22">Hereu P</searchLink>; Faculty of Medicine and Health Sciences, Universitat de Barcelona, Barcelona, Spain.; Department of Clinical Pharmacology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Clinical Research and Clinical Trial Unit (UICEC-IDIBELL), Spanish Clinical Research Network, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Corbella+X%22">Corbella X</searchLink>; Department of Internal Medicine, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; School of Medicine, Universitat Internacional de Catalunya, Barcelona, Spain.
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