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The NHance® Mutation-Equipped Anti-MET Antibody ARGX-111 Displays Increased Tissue Penetration and Anti-Tumor Activity in Advanced Cancer Patients.

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Title: The NHance® Mutation-Equipped Anti-MET Antibody ARGX-111 Displays Increased Tissue Penetration and Anti-Tumor Activity in Advanced Cancer Patients.
Authors: Aftimos P; Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium., Rolfo C; University Hospital Antwerp, 2650 Edegem, Belgium., Rottey S; University Hospital Ghent, 9000 Ghent, Belgium., Barthélémy P; Medical Oncology Unit, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France., Borg C; Medical Oncology Department, University Hospital of Besançon, CEDEX, 25000 Besançon, France., Park K; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea., Oh DY; Seoul National University Hospital, Seoul 03080, Korea., Kim SW; Asan Medical Center, Department of Oncology, University of Ulsan College of Medicine, Seoul 05505, Korea., De Jonge N; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., Hanssens V; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., Zwanenpoel K; University Hospital Antwerp, 2650 Edegem, Belgium., Molthoff C; Department of Radiology & Nuclear Medicine, VU University Medical Center Amsterdam, 1012 Amsterdam, The Netherlands., Vugts D; Department of Radiology & Nuclear Medicine, VU University Medical Center Amsterdam, 1012 Amsterdam, The Netherlands., Dreier T; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.; AgomAb Therapeutics NV, 9000 Ghent, Belgium., Verheesen P; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., van Dongen GAMS; Department of Radiology & Nuclear Medicine, VU University Medical Center Amsterdam, 1012 Amsterdam, The Netherlands., Jacobs J; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., Van Rompaey L; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., Hultberg A; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., Michieli P; AgomAb Therapeutics NV, 9000 Ghent, Belgium.; Department of Oncology, University of Torino Medical School, 10124 Turin, Italy., Pauwels P; University Hospital Antwerp, 2650 Edegem, Belgium., Fung S; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., Thibault A; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., de Haard H; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., Leupin N; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium., Awada A; Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium.
Source: Biomedicines [Biomedicines] 2021 Jun 10; Vol. 9 (6). Date of Electronic Publication: 2021 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE
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  Data: The NHance<superscript>®</superscript> Mutation-Equipped Anti-MET Antibody ARGX-111 Displays Increased Tissue Penetration and Anti-Tumor Activity in Advanced Cancer Patients.
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  Data: <searchLink fieldCode="AU" term="%22Aftimos+P%22">Aftimos P</searchLink>; Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Rolfo+C%22">Rolfo C</searchLink>; University Hospital Antwerp, 2650 Edegem, Belgium.<br /><searchLink fieldCode="AU" term="%22Rottey+S%22">Rottey S</searchLink>; University Hospital Ghent, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Barthélémy+P%22">Barthélémy P</searchLink>; Medical Oncology Unit, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Borg+C%22">Borg C</searchLink>; Medical Oncology Department, University Hospital of Besançon, CEDEX, 25000 Besançon, France.<br /><searchLink fieldCode="AU" term="%22Park+K%22">Park K</searchLink>; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.<br /><searchLink fieldCode="AU" term="%22Oh+DY%22">Oh DY</searchLink>; Seoul National University Hospital, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SW%22">Kim SW</searchLink>; Asan Medical Center, Department of Oncology, University of Ulsan College of Medicine, Seoul 05505, Korea.<br /><searchLink fieldCode="AU" term="%22De+Jonge+N%22">De Jonge N</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Hanssens+V%22">Hanssens V</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Zwanenpoel+K%22">Zwanenpoel K</searchLink>; University Hospital Antwerp, 2650 Edegem, Belgium.<br /><searchLink fieldCode="AU" term="%22Molthoff+C%22">Molthoff C</searchLink>; Department of Radiology & Nuclear Medicine, VU University Medical Center Amsterdam, 1012 Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vugts+D%22">Vugts D</searchLink>; Department of Radiology & Nuclear Medicine, VU University Medical Center Amsterdam, 1012 Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dreier+T%22">Dreier T</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.; AgomAb Therapeutics NV, 9000 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Verheesen+P%22">Verheesen P</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22van+Dongen+GAMS%22">van Dongen GAMS</searchLink>; Department of Radiology & Nuclear Medicine, VU University Medical Center Amsterdam, 1012 Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jacobs+J%22">Jacobs J</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Rompaey+L%22">Van Rompaey L</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Hultberg+A%22">Hultberg A</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Michieli+P%22">Michieli P</searchLink>; AgomAb Therapeutics NV, 9000 Ghent, Belgium.; Department of Oncology, University of Torino Medical School, 10124 Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Pauwels+P%22">Pauwels P</searchLink>; University Hospital Antwerp, 2650 Edegem, Belgium.<br /><searchLink fieldCode="AU" term="%22Fung+S%22">Fung S</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Thibault+A%22">Thibault A</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22de+Haard+H%22">de Haard H</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Leupin+N%22">Leupin N</searchLink>; Argenx BV, Industriepark Zwijnaarde 7, 9052 Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Awada+A%22">Awada A</searchLink>; Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Brussels, Belgium.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101691304 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2227-9059 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222279059%22">22279059 </searchLink><i>NLM ISO Abbreviation: </i>Biomedicines <i>Subsets: </i>PubMed not MEDLINE
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