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No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study.

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Title: No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study.
Authors: Dominguez-Valentin M; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK., Plazzer JP; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Department of Medicine, Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, VIC 3050, Australia., Sampson JR; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; Institute of Medical Genetics, Division of Cancer and Genetics, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK., Engel C; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107 Leipzig, Germany., Aretz S; Institute of Human Genetics, National Center for Hereditary Tumor Syndromes, Medical Faculty, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany., Jenkins MA; Melbourne School of Population and Global Health, Centre for Epidemiology and Biostatistics, The University of Melbourne, Parkville, VIC 3010, Australia., Sunde L; Department of Clinical Genetics, Aalborg University Hospital, 9000 Aalborg, Denmark.; Department of Biomedicine, Aarhus University, DK-8000 Aarhus, Denmark., Bernstein I; Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg University, 9100 Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University Hospital, Aalborg University, 9100 Aalborg, Denmark., Capella G; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L, Hospitalet de Llobregat, 08908 Barcelona, Spain., Balaguer F; Gastroenterology Department, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08036 Barcelona, Spain., Macrae F; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Department of Medicine, Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, VIC 3050, Australia., Winship IM; Department of Genomic Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC 3052, Australia.; Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC 3052, Australia., Thomas H; Department of Surgery and Cancer, St Mark's Hospital, Imperial College London, London HA1 3UJ, UK., Evans DG; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK., Burn J; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK., Greenblatt M; Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., de Vos Tot Nederveen Cappel WH; Department of Gastroenterology and Hepatology, Isala Clinics, 8015 Zwolle, The Netherlands., Sijmons RH; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Department of Genetics, University Medical Center Groningen, University of Groningen, 9713GZ Groningen, The Netherlands., Nielsen M; Department of Clinical Genetics, Leids Universitair Medisch Centrum, 2300RC Leiden, The Netherlands., Bertario L; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, IRCCS, 20141 Milan, Italy., Bonanni B; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology, IRCCS, 20141 Milan, Italy., Tibiletti MG; Ospedale di Circolo ASST Settelaghi, Centro di Ricerca Tumori Eredo-Familiari, Università dell'Insubria, 21100 Varese, Italy., Cavestro GM; Gastroenterology and Gastrointestinal Endoscopy Unit, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, 20132 Milan, Italy., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76 Stockholm, Sweden., Valle AD; Grupo Colaborativo Uruguayo, Investigación de Afecciones Oncológicas Hereditarias (GCU), Hospital Fuerzas Armadas, Montevideo 11600, Uruguay., Lopez-Kostner F; Programa Cáncer Heredo Familiar, Clínica Universidad de los Andes, Santiago 7550000, Chile., Alvarez K; Programa Cáncer Heredo Familiar, Clínica Universidad de los Andes, Santiago 7550000, Chile., Gluck N; Department of Gastroenterology, Sackler Faculty of Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv 64259, Israel., Katz L; The Department of Gastroenterology, Gastro-Oncology Unit, High Risk and GI Cancer Prevention Clinic, Sheba Medical Center, Sheba 91120, Israel., Heinimann K; Medical Genetics, Institute for Medical Genetics and Pathology, University Hospital Basel, 4031 Basel, Switzerland., Vaccaro CA; Hereditary Cancer Program (PROCANHE), Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.; Instituto de Medicina Traslacional e Ingenieria Biomedica (IMTIB), CONICET IU, Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina., Nakken S; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.; Centre for Cancer Cell Reprogramming (CanCell), Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 4950 Oslo, Norway., Hovig E; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.; Department of Informatics, Centre for Bioinformatics, University of Oslo, 0316 Oslo, Norway., Green K; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK., Lalloo F; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK., Hill J; Department of Surgery, Central Manchester University Hospitals NHS, Foundation Trust, University of Manchester, London M13 9WL, UK., Vasen HFA; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, 2333 Leiden, The Netherlands., Perne C; Institute of Human Genetics, National Center for Hereditary Tumor Syndromes, Medical Faculty, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany., Büttner R; Institute of Pathology, University of Cologne, 50937 Cologne, Germany., Görgens H; Department of Surgery, Technische Universität Dresden, 01062 Dresden, Germany., Holinski-Feder E; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 Munich, Germany.; Center of Medical Genetics, 80335 Munich, Germany., Morak M; Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 Munich, Germany.; Center of Medical Genetics, 80335 Munich, Germany., Holzapfel S; Institute of Human Genetics, National Center for Hereditary Tumor Syndromes, Medical Faculty, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany., Hüneburg R; Department of Internal Medicine, University Hospital Bonn, 53127 Bonn, Germany., von Knebel Doeberitz M; Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.; Cooperation Unit Applied Tumour Biology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107 Leipzig, Germany., Rahner N; Medical School, Institute of Human Genetics, Heinrich-Heine-University, 40225 Dusseldorf, Germany., Weitz J; Department of Surgery, Technische Universität Dresden, 01062 Dresden, Germany., Steinke-Lange V; Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 Munich, Germany.; Center of Medical Genetics, 80335 Munich, Germany., Schmiegel W; Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, D-44789 Bochum, Germany., Vangala D; Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, D-44789 Bochum, Germany., Crosbie EJ; Gynaecological Oncology Research Group, Manchester University NHS Foundation Trust, Manchester, UK and Division of Cancer Sciences, University of Manchester, Manchester M20 4GJ, UK., Pineda M; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L, Hospitalet de Llobregat, 08908 Barcelona, Spain., Navarro M; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L, Hospitalet de Llobregat, 08908 Barcelona, Spain., Brunet J; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L, Hospitalet de Llobregat, 08908 Barcelona, Spain., Moreira L; Gastroenterology Department, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08036 Barcelona, Spain., Sánchez A; Gastroenterology Department, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08036 Barcelona, Spain., Serra-Burriel M; Centre de Recerca en Economia i Salut (CRES-UPF), Universitat de Barcelona, 08002 Barcelona, Spain., Mints M; Division of Obstetrics and Gyneacology, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Solna, 171 77 Stockholm, Sweden., Kariv R; Department of Gastroenterology, Sackler Faculty of Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv 64259, Israel., Rosner G; Department of Gastroenterology, Sackler Faculty of Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv 64259, Israel., Piñero TA; Hereditary Cancer Program (PROCANHE), Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.; Instituto de Medicina Traslacional e Ingenieria Biomedica (IMTIB), CONICET IU, Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina., Pavicic WH; Hereditary Cancer Program (PROCANHE), Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.; Instituto de Medicina Traslacional e Ingenieria Biomedica (IMTIB), CONICET IU, Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina., Kalfayan P; Hereditary Cancer Program (PROCANHE), Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina., Broeke SWT; Department of Clinical Genetics, Leids Universitair Medisch Centrum, 2300RC Leiden, The Netherlands., Mecklin JP; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Departments of Surgery, Central Finland Hospital Nova, University of Jyväskylä, 40620 Jyväskylä, Finland., Pylvänäinen K; Department of Education and Science, Sport and Health Sciences, Central Finland Hospital Nova, University of Jyväskylä, FI-40014 Jyväskylä, Finland., Renkonen-Sinisalo L; Applied Tumour Genomics Research Program, University of Helsinki, 00014 Helsinki, Finland.; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, 00280 Helsinki, Finland., Lepistö A; Applied Tumour Genomics Research Program, University of Helsinki, 00014 Helsinki, Finland.; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, 00280 Helsinki, Finland., Peltomäki P; Department of Medical and Clinical Genetics, University of Helsinki, 00014 Helsinki, Finland., Hopper JL; Melbourne School of Population and Global Health, Centre for Epidemiology and Biostatistics, The University of Melbourne, Parkville, VIC 3010, Australia., Win AK; Melbourne School of Population and Global Health, Centre for Epidemiology and Biostatistics, The University of Melbourne, Parkville, VIC 3010, Australia., Buchanan DD; Centre for Cancer Research, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC 3010, Australia.; Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Parkville, VIC 3010, Australia.; Genomic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, Parkville, VIC 3010, Australia., Lindor NM; Department of Health Science Research, Mayo Clinic Arizona, Phoenix, AZ 85054, USA., Gallinger S; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON M5G 1X5, Canada., Marchand LL; Cancer Center, University of Hawaii, Honolulu, HI 96813, USA., Newcomb PA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA., Figueiredo JC; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Thibodeau SN; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Therkildsen C; The Danish HNPCC Register, Clinical Research Centre, Copenhagen University Hospital, 2560 Hvidovre, Denmark., Hansen TVO; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark., Lindberg L; Gastro Unit, Copenhagen University Hospital, 2560 Hvidovre, Denmark., Rødland EA; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway., Neffa F; Grupo Colaborativo Uruguayo, Investigación de Afecciones Oncológicas Hereditarias (GCU), Hospital Fuerzas Armadas, Montevideo 11600, Uruguay., Esperon P; Grupo Colaborativo Uruguayo, Investigación de Afecciones Oncológicas Hereditarias (GCU), Hospital Fuerzas Armadas, Montevideo 11600, Uruguay., Tjandra D; Department of Medicine, Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, VIC 3050, Australia.; Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC 3052, Australia., Möslein G; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Surgical Center for Hereditary Tumors, Ev. Bethesda Khs Duisburg, University Witten-Herdecke, 58448 Herdecke, Germany., Seppälä TT; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, 00280 Helsinki, Finland.; Department of Surgical Oncology, Johns Hopkins Hospital, Baltimore, MA 21287, USA., Møller P; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.
Source: Journal of clinical medicine [J Clin Med] 2021 Jun 28; Vol. 10 (13). Date of Electronic Publication: 2021 Jun 28.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Dominguez-Valentin+M%22">Dominguez-Valentin M</searchLink>; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.<br /><searchLink fieldCode="AU" term="%22Plazzer+JP%22">Plazzer JP</searchLink>; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Department of Medicine, Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, VIC 3050, Australia.<br /><searchLink fieldCode="AU" term="%22Sampson+JR%22">Sampson JR</searchLink>; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; Institute of Medical Genetics, Division of Cancer and Genetics, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Engel+C%22">Engel C</searchLink>; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107 Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Aretz+S%22">Aretz S</searchLink>; Institute of Human Genetics, National Center for Hereditary Tumor Syndromes, Medical Faculty, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Jenkins+MA%22">Jenkins MA</searchLink>; Melbourne School of Population and Global Health, Centre for Epidemiology and Biostatistics, The University of Melbourne, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Sunde+L%22">Sunde L</searchLink>; Department of Clinical Genetics, Aalborg University Hospital, 9000 Aalborg, Denmark.; Department of Biomedicine, Aarhus University, DK-8000 Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Bernstein+I%22">Bernstein I</searchLink>; Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg University, 9100 Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University Hospital, Aalborg University, 9100 Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Capella+G%22">Capella G</searchLink>; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L, Hospitalet de Llobregat, 08908 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Balaguer+F%22">Balaguer F</searchLink>; Gastroenterology Department, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Macrae+F%22">Macrae F</searchLink>; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Department of Medicine, Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, VIC 3050, Australia.<br /><searchLink fieldCode="AU" term="%22Winship+IM%22">Winship IM</searchLink>; Department of Genomic Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC 3052, Australia.; Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Thomas+H%22">Thomas H</searchLink>; Department of Surgery and Cancer, St Mark's Hospital, Imperial College London, London HA1 3UJ, UK.<br /><searchLink fieldCode="AU" term="%22Evans+DG%22">Evans DG</searchLink>; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.<br /><searchLink fieldCode="AU" term="%22Burn+J%22">Burn J</searchLink>; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.<br /><searchLink fieldCode="AU" term="%22Greenblatt+M%22">Greenblatt M</searchLink>; Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.<br /><searchLink fieldCode="AU" term="%22de+Vos+Tot+Nederveen+Cappel+WH%22">de Vos Tot Nederveen Cappel WH</searchLink>; Department of Gastroenterology and Hepatology, Isala Clinics, 8015 Zwolle, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sijmons+RH%22">Sijmons RH</searchLink>; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Department of Genetics, University Medical Center Groningen, University of Groningen, 9713GZ Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nielsen+M%22">Nielsen M</searchLink>; Department of Clinical Genetics, Leids Universitair Medisch Centrum, 2300RC Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bertario+L%22">Bertario L</searchLink>; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, IRCCS, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bonanni+B%22">Bonanni B</searchLink>; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology, IRCCS, 20141 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tibiletti+MG%22">Tibiletti MG</searchLink>; Ospedale di Circolo ASST Settelaghi, Centro di Ricerca Tumori Eredo-Familiari, Università dell'Insubria, 21100 Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Cavestro+GM%22">Cavestro GM</searchLink>; Gastroenterology and Gastrointestinal Endoscopy Unit, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lindblom+A%22">Lindblom A</searchLink>; Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Valle+AD%22">Valle AD</searchLink>; Grupo Colaborativo Uruguayo, Investigación de Afecciones Oncológicas Hereditarias (GCU), Hospital Fuerzas Armadas, Montevideo 11600, Uruguay.<br /><searchLink fieldCode="AU" term="%22Lopez-Kostner+F%22">Lopez-Kostner F</searchLink>; Programa Cáncer Heredo Familiar, Clínica Universidad de los Andes, Santiago 7550000, Chile.<br /><searchLink fieldCode="AU" term="%22Alvarez+K%22">Alvarez K</searchLink>; Programa Cáncer Heredo Familiar, Clínica Universidad de los Andes, Santiago 7550000, Chile.<br /><searchLink fieldCode="AU" term="%22Gluck+N%22">Gluck N</searchLink>; Department of Gastroenterology, Sackler Faculty of Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv 64259, Israel.<br /><searchLink fieldCode="AU" term="%22Katz+L%22">Katz L</searchLink>; The Department of Gastroenterology, Gastro-Oncology Unit, High Risk and GI Cancer Prevention Clinic, Sheba Medical Center, Sheba 91120, Israel.<br /><searchLink fieldCode="AU" term="%22Heinimann+K%22">Heinimann K</searchLink>; Medical Genetics, Institute for Medical Genetics and Pathology, University Hospital Basel, 4031 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vaccaro+CA%22">Vaccaro CA</searchLink>; Hereditary Cancer Program (PROCANHE), Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.; Instituto de Medicina Traslacional e Ingenieria Biomedica (IMTIB), CONICET IU, Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.<br /><searchLink fieldCode="AU" term="%22Nakken+S%22">Nakken S</searchLink>; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.; Centre for Cancer Cell Reprogramming (CanCell), Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 4950 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Hovig+E%22">Hovig E</searchLink>; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.; Department of Informatics, Centre for Bioinformatics, University of Oslo, 0316 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Green+K%22">Green K</searchLink>; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.<br /><searchLink fieldCode="AU" term="%22Lalloo+F%22">Lalloo F</searchLink>; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.<br /><searchLink fieldCode="AU" term="%22Hill+J%22">Hill J</searchLink>; Department of Surgery, Central Manchester University Hospitals NHS, Foundation Trust, University of Manchester, London M13 9WL, UK.<br /><searchLink fieldCode="AU" term="%22Vasen+HFA%22">Vasen HFA</searchLink>; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, 2333 Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Perne+C%22">Perne C</searchLink>; Institute of Human Genetics, National Center for Hereditary Tumor Syndromes, Medical Faculty, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Büttner+R%22">Büttner R</searchLink>; Institute of Pathology, University of Cologne, 50937 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Görgens+H%22">Görgens H</searchLink>; Department of Surgery, Technische Universität Dresden, 01062 Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Holinski-Feder+E%22">Holinski-Feder E</searchLink>; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 Munich, Germany.; Center of Medical Genetics, 80335 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Morak+M%22">Morak M</searchLink>; Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 Munich, Germany.; Center of Medical Genetics, 80335 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Holzapfel+S%22">Holzapfel S</searchLink>; Institute of Human Genetics, National Center for Hereditary Tumor Syndromes, Medical Faculty, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hüneburg+R%22">Hüneburg R</searchLink>; Department of Internal Medicine, University Hospital Bonn, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22von+Knebel+Doeberitz+M%22">von Knebel Doeberitz M</searchLink>; Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.; Cooperation Unit Applied Tumour Biology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Loeffler+M%22">Loeffler M</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107 Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Rahner+N%22">Rahner N</searchLink>; Medical School, Institute of Human Genetics, Heinrich-Heine-University, 40225 Dusseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Weitz+J%22">Weitz J</searchLink>; Department of Surgery, Technische Universität Dresden, 01062 Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Steinke-Lange+V%22">Steinke-Lange V</searchLink>; Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 Munich, Germany.; Center of Medical Genetics, 80335 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schmiegel+W%22">Schmiegel W</searchLink>; Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, D-44789 Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Vangala+D%22">Vangala D</searchLink>; Department of Medicine, Knappschaftskrankenhaus, Ruhr-University Bochum, D-44789 Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Crosbie+EJ%22">Crosbie EJ</searchLink>; Gynaecological Oncology Research Group, Manchester University NHS Foundation Trust, Manchester, UK and Division of Cancer Sciences, University of Manchester, Manchester M20 4GJ, UK.<br /><searchLink fieldCode="AU" term="%22Pineda+M%22">Pineda M</searchLink>; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L, Hospitalet de Llobregat, 08908 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Navarro+M%22">Navarro M</searchLink>; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L, Hospitalet de Llobregat, 08908 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Brunet+J%22">Brunet J</searchLink>; Hereditary Cancer Program, Institut Català d'Oncologia-IDIBELL, L, Hospitalet de Llobregat, 08908 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Moreira+L%22">Moreira L</searchLink>; Gastroenterology Department, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez+A%22">Sánchez A</searchLink>; Gastroenterology Department, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, 08036 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Serra-Burriel+M%22">Serra-Burriel M</searchLink>; Centre de Recerca en Economia i Salut (CRES-UPF), Universitat de Barcelona, 08002 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mints+M%22">Mints M</searchLink>; Division of Obstetrics and Gyneacology, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Solna, 171 77 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Kariv+R%22">Kariv R</searchLink>; Department of Gastroenterology, Sackler Faculty of Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv 64259, Israel.<br /><searchLink fieldCode="AU" term="%22Rosner+G%22">Rosner G</searchLink>; Department of Gastroenterology, Sackler Faculty of Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv 64259, Israel.<br /><searchLink fieldCode="AU" term="%22Piñero+TA%22">Piñero TA</searchLink>; Hereditary Cancer Program (PROCANHE), Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.; Instituto de Medicina Traslacional e Ingenieria Biomedica (IMTIB), CONICET IU, Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.<br /><searchLink fieldCode="AU" term="%22Pavicic+WH%22">Pavicic WH</searchLink>; Hereditary Cancer Program (PROCANHE), Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.; Instituto de Medicina Traslacional e Ingenieria Biomedica (IMTIB), CONICET IU, Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.<br /><searchLink fieldCode="AU" term="%22Kalfayan+P%22">Kalfayan P</searchLink>; Hereditary Cancer Program (PROCANHE), Hospital Italiano de Buenos Aires, Buenos Aires C1199ABB, Argentina.<br /><searchLink fieldCode="AU" term="%22Broeke+SWT%22">Broeke SWT</searchLink>; Department of Clinical Genetics, Leids Universitair Medisch Centrum, 2300RC Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mecklin+JP%22">Mecklin JP</searchLink>; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Departments of Surgery, Central Finland Hospital Nova, University of Jyväskylä, 40620 Jyväskylä, Finland.<br /><searchLink fieldCode="AU" term="%22Pylvänäinen+K%22">Pylvänäinen K</searchLink>; Department of Education and Science, Sport and Health Sciences, Central Finland Hospital Nova, University of Jyväskylä, FI-40014 Jyväskylä, Finland.<br /><searchLink fieldCode="AU" term="%22Renkonen-Sinisalo+L%22">Renkonen-Sinisalo L</searchLink>; Applied Tumour Genomics Research Program, University of Helsinki, 00014 Helsinki, Finland.; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, 00280 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Lepistö+A%22">Lepistö A</searchLink>; Applied Tumour Genomics Research Program, University of Helsinki, 00014 Helsinki, Finland.; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, 00280 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Peltomäki+P%22">Peltomäki P</searchLink>; Department of Medical and Clinical Genetics, University of Helsinki, 00014 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hopper+JL%22">Hopper JL</searchLink>; Melbourne School of Population and Global Health, Centre for Epidemiology and Biostatistics, The University of Melbourne, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Win+AK%22">Win AK</searchLink>; Melbourne School of Population and Global Health, Centre for Epidemiology and Biostatistics, The University of Melbourne, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Buchanan+DD%22">Buchanan DD</searchLink>; Centre for Cancer Research, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC 3010, Australia.; Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Parkville, VIC 3010, Australia.; Genomic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Lindor+NM%22">Lindor NM</searchLink>; Department of Health Science Research, Mayo Clinic Arizona, Phoenix, AZ 85054, USA.<br /><searchLink fieldCode="AU" term="%22Gallinger+S%22">Gallinger S</searchLink>; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON M5G 1X5, Canada.<br /><searchLink fieldCode="AU" term="%22Marchand+LL%22">Marchand LL</searchLink>; Cancer Center, University of Hawaii, Honolulu, HI 96813, USA.<br /><searchLink fieldCode="AU" term="%22Newcomb+PA%22">Newcomb PA</searchLink>; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.<br /><searchLink fieldCode="AU" term="%22Figueiredo+JC%22">Figueiredo JC</searchLink>; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.<br /><searchLink fieldCode="AU" term="%22Thibodeau+SN%22">Thibodeau SN</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Therkildsen+C%22">Therkildsen C</searchLink>; The Danish HNPCC Register, Clinical Research Centre, Copenhagen University Hospital, 2560 Hvidovre, Denmark.<br /><searchLink fieldCode="AU" term="%22Hansen+TVO%22">Hansen TVO</searchLink>; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lindberg+L%22">Lindberg L</searchLink>; Gastro Unit, Copenhagen University Hospital, 2560 Hvidovre, Denmark.<br /><searchLink fieldCode="AU" term="%22Rødland+EA%22">Rødland EA</searchLink>; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Neffa+F%22">Neffa F</searchLink>; Grupo Colaborativo Uruguayo, Investigación de Afecciones Oncológicas Hereditarias (GCU), Hospital Fuerzas Armadas, Montevideo 11600, Uruguay.<br /><searchLink fieldCode="AU" term="%22Esperon+P%22">Esperon P</searchLink>; Grupo Colaborativo Uruguayo, Investigación de Afecciones Oncológicas Hereditarias (GCU), Hospital Fuerzas Armadas, Montevideo 11600, Uruguay.<br /><searchLink fieldCode="AU" term="%22Tjandra+D%22">Tjandra D</searchLink>; Department of Medicine, Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, VIC 3050, Australia.; Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Möslein+G%22">Möslein G</searchLink>; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Surgical Center for Hereditary Tumors, Ev. Bethesda Khs Duisburg, University Witten-Herdecke, 58448 Herdecke, Germany.<br /><searchLink fieldCode="AU" term="%22Seppälä+TT%22">Seppälä TT</searchLink>; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, 00280 Helsinki, Finland.; Department of Surgical Oncology, Johns Hopkins Hospital, Baltimore, MA 21287, USA.<br /><searchLink fieldCode="AU" term="%22Møller+P%22">Møller P</searchLink>; Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, 0379 Oslo, Norway.; European Hereditary Tumour Group (EHTG), c/o Lindsays, Caledonian Exchange 19A Canning Street, Edinburgh EH3 8HE, UK.; The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), The Polyposis Registry, St Mark's Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, UK.
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  Data: <searchLink fieldCode="JN" term="%22101606588%22">Journal of clinical medicine</searchLink> [J Clin Med] 2021 Jun 28; Vol. 10 (13). <i>Date of Electronic Publication: </i>2021 Jun 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101606588 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2077-0383 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220770383%22">20770383 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Med <i>Subsets: </i>PubMed not MEDLINE
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      – TitleFull: No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study.
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            NameFull: Gallinger S
      – PersonEntity:
          Name:
            NameFull: Marchand LL
      – PersonEntity:
          Name:
            NameFull: Newcomb PA
      – PersonEntity:
          Name:
            NameFull: Figueiredo JC
      – PersonEntity:
          Name:
            NameFull: Thibodeau SN
      – PersonEntity:
          Name:
            NameFull: Therkildsen C
      – PersonEntity:
          Name:
            NameFull: Hansen TVO
      – PersonEntity:
          Name:
            NameFull: Lindberg L
      – PersonEntity:
          Name:
            NameFull: Rødland EA
      – PersonEntity:
          Name:
            NameFull: Neffa F
      – PersonEntity:
          Name:
            NameFull: Esperon P
      – PersonEntity:
          Name:
            NameFull: Tjandra D
      – PersonEntity:
          Name:
            NameFull: Möslein G
      – PersonEntity:
          Name:
            NameFull: Seppälä TT
      – PersonEntity:
          Name:
            NameFull: Møller P
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 28
              M: 06
              Text: 2021 Jun 28
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 2077-0383
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 13
          Titles:
            – TitleFull: Journal of clinical medicine
              Type: main
ResultId 1