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Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo.

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Title: Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo.
Authors: Winterberg D; ALL-BFM Study Group, Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Arnold-Heller Str. 3, Haus C, 24105 Kiel, Germany.; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany., Lenk L; ALL-BFM Study Group, Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Arnold-Heller Str. 3, Haus C, 24105 Kiel, Germany., Oßwald M; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany., Vogiatzi F; ALL-BFM Study Group, Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Arnold-Heller Str. 3, Haus C, 24105 Kiel, Germany., Gehlert CL; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany., Frielitz FS; Institute for Social Medicine and Epidemiology, University of Lübeck, 23538 Lübeck, Germany., Klausz K; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany., Rösner T; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany., Valerius T; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany., Trauzold A; Institute for Experimental Cancer Research, Christian-Albrechts-University Kiel, 24104 Kiel, Germany., Peipp M; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany., Kellner C; Department of Transfusion Medicine, Cell Therapeutics and Hemostaseology, LMU University Hospital Munich, 81377 Munich, Germany., Schewe DM; ALL-BFM Study Group, Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Arnold-Heller Str. 3, Haus C, 24105 Kiel, Germany.
Source: Journal of clinical medicine [J Clin Med] 2021 Jun 15; Vol. 10 (12). Date of Electronic Publication: 2021 Jun 15.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo.
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  Data: <searchLink fieldCode="AU" term="%22Winterberg+D%22">Winterberg D</searchLink>; ALL-BFM Study Group, Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Arnold-Heller Str. 3, Haus C, 24105 Kiel, Germany.; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Lenk+L%22">Lenk L</searchLink>; ALL-BFM Study Group, Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Arnold-Heller Str. 3, Haus C, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Oßwald+M%22">Oßwald M</searchLink>; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Vogiatzi+F%22">Vogiatzi F</searchLink>; ALL-BFM Study Group, Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Arnold-Heller Str. 3, Haus C, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Gehlert+CL%22">Gehlert CL</searchLink>; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Frielitz+FS%22">Frielitz FS</searchLink>; Institute for Social Medicine and Epidemiology, University of Lübeck, 23538 Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Klausz+K%22">Klausz K</searchLink>; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Rösner+T%22">Rösner T</searchLink>; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Valerius+T%22">Valerius T</searchLink>; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Trauzold+A%22">Trauzold A</searchLink>; Institute for Experimental Cancer Research, Christian-Albrechts-University Kiel, 24104 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Peipp+M%22">Peipp M</searchLink>; Department of Medicine II Christian-Albrechts, Division of Stem Cell Transplantation and Immunotherapy, Campus Kiel, University Kiel and University Hospital Schleswig-Holstein, 24105 Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Kellner+C%22">Kellner C</searchLink>; Department of Transfusion Medicine, Cell Therapeutics and Hemostaseology, LMU University Hospital Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schewe+DM%22">Schewe DM</searchLink>; ALL-BFM Study Group, Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Arnold-Heller Str. 3, Haus C, 24105 Kiel, Germany.
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      – TitleFull: Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo.
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