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Genome-Wide Analysis Reveals Hypoxic Microenvironment Is Associated With Immunosuppression in Poor Survival of Stage II/III Colorectal Cancer Patients.

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Title: Genome-Wide Analysis Reveals Hypoxic Microenvironment Is Associated With Immunosuppression in Poor Survival of Stage II/III Colorectal Cancer Patients.
Authors: Chen YF; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Yu ZL; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Lv MY; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Zheng B; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Tan YX; The First Hospital of Lanzhou University, Lanzhou, China., Ke J; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Liu XH; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Cai ZR; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Zou YF; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Lan P; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Wu XJ; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China., Gao F; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.
Source: Frontiers in medicine [Front Med (Lausanne)] 2021 Jun 15; Vol. 8, pp. 686885. Date of Electronic Publication: 2021 Jun 15 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome-Wide Analysis Reveals Hypoxic Microenvironment Is Associated With Immunosuppression in Poor Survival of Stage II/III Colorectal Cancer Patients.
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  Data: <searchLink fieldCode="AU" term="%22Chen+YF%22">Chen YF</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yu+ZL%22">Yu ZL</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lv+MY%22">Lv MY</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+B%22">Zheng B</searchLink>; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Tan+YX%22">Tan YX</searchLink>; The First Hospital of Lanzhou University, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Ke+J%22">Ke J</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+XH%22">Liu XH</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Cai+ZR%22">Cai ZR</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zou+YF%22">Zou YF</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lan+P%22">Lan P</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+XJ%22">Wu XJ</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Gao+F%22">Gao F</searchLink>; Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Guangdong Institute of Gastroenterology, Guangzhou, China.
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        Value: 10.3389/fmed.2021.686885
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