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Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity.

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Title: Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity.
Authors: Jayashankar V; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA., Selwan E; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA., Hancock SE; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia., Verlande A; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA., Goodson MO; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA., Eckenstein KH; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA., Milinkeviciute G; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, USA., Hoover BM; Division of Hematology/Oncology, Department of Medicine, University of California, Irvine, CA, USA., Chen B; Department of Chemistry, Université de Montréal, Montréal, QC, Canada., Fleischman AG; Division of Hematology/Oncology, Department of Medicine, University of California, Irvine, CA, USA., Cramer KS; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, USA., Hanessian S; Department of Chemistry, Université de Montréal, Montréal, QC, Canada., Masri S; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA., Turner N; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia., Edinger AL; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.
Source: EMBO molecular medicine [EMBO Mol Med] 2021 Aug 09; Vol. 13 (8), pp. e13086. Date of Electronic Publication: 2021 Jul 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity.
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  Data: <searchLink fieldCode="AU" term="%22Jayashankar+V%22">Jayashankar V</searchLink>; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Selwan+E%22">Selwan E</searchLink>; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hancock+SE%22">Hancock SE</searchLink>; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Verlande+A%22">Verlande A</searchLink>; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Goodson+MO%22">Goodson MO</searchLink>; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Eckenstein+KH%22">Eckenstein KH</searchLink>; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Milinkeviciute+G%22">Milinkeviciute G</searchLink>; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hoover+BM%22">Hoover BM</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+B%22">Chen B</searchLink>; Department of Chemistry, Université de Montréal, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Fleischman+AG%22">Fleischman AG</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cramer+KS%22">Cramer KS</searchLink>; Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hanessian+S%22">Hanessian S</searchLink>; Department of Chemistry, Université de Montréal, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Masri+S%22">Masri S</searchLink>; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Turner+N%22">Turner N</searchLink>; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Edinger+AL%22">Edinger AL</searchLink>; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2021 Aug 09; Vol. 13 (8), pp. e13086. <i>Date of Electronic Publication: </i>2021 Jul 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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