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Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses.

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Title: Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses.
Authors: Jairaman A; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Othy S; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Dynes JL; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Yeromin AV; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Zavala A; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Greenberg ML; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Nourse JL; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA., Holt JR; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA., Cahalan SM; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.; Vertex Pharmaceuticals, 3215 Merryfield Row, San Diego, CA 92121, USA., Marangoni F; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Parker I; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA., Pathak MM; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA.; Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA.; Center for Complex Systems Biology, University of California, Irvine, CA 92697, USA., Cahalan MD; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA. mcahalan@uci.edu.; Institute for Immunology, University of California, Irvine, CA 92697, USA.
Source: Science advances [Sci Adv] 2021 Jul 07; Vol. 7 (28). Date of Electronic Publication: 2021 Jul 07 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4<superscript>+</superscript> T cell responses.
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  Data: <searchLink fieldCode="AU" term="%22Jairaman+A%22">Jairaman A</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.<br /><searchLink fieldCode="AU" term="%22Othy+S%22">Othy S</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.<br /><searchLink fieldCode="AU" term="%22Dynes+JL%22">Dynes JL</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.<br /><searchLink fieldCode="AU" term="%22Yeromin+AV%22">Yeromin AV</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.<br /><searchLink fieldCode="AU" term="%22Zavala+A%22">Zavala A</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.<br /><searchLink fieldCode="AU" term="%22Greenberg+ML%22">Greenberg ML</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.<br /><searchLink fieldCode="AU" term="%22Nourse+JL%22">Nourse JL</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Holt+JR%22">Holt JR</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Cahalan+SM%22">Cahalan SM</searchLink>; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.; Vertex Pharmaceuticals, 3215 Merryfield Row, San Diego, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Marangoni+F%22">Marangoni F</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.<br /><searchLink fieldCode="AU" term="%22Parker+I%22">Parker I</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Pathak+MM%22">Pathak MM</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA.; Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA.; Center for Complex Systems Biology, University of California, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Cahalan+MD%22">Cahalan MD</searchLink>; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA. mcahalan@uci.edu.; Institute for Immunology, University of California, Irvine, CA 92697, USA.
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  Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2021 Jul 07; Vol. 7 (28). <i>Date of Electronic Publication: </i>2021 Jul 07 (<i>Print Publication: </i>2021).
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