Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses.
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| Title: | Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses. |
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| Authors: | Jairaman A; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Othy S; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Dynes JL; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Yeromin AV; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Zavala A; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Greenberg ML; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Nourse JL; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA., Holt JR; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA., Cahalan SM; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.; Vertex Pharmaceuticals, 3215 Merryfield Row, San Diego, CA 92121, USA., Marangoni F; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA., Parker I; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA., Pathak MM; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA 92697, USA.; Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA.; Center for Complex Systems Biology, University of California, Irvine, CA 92697, USA., Cahalan MD; Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4561, USA. mcahalan@uci.edu.; Institute for Immunology, University of California, Irvine, CA 92697, USA. |
| Source: | Science advances [Sci Adv] 2021 Jul 07; Vol. 7 (28). Date of Electronic Publication: 2021 Jul 07 (Print Publication: 2021). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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