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24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation.

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Title: 24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation.
Authors: Zhu C; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Boucheron N; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. Electronic address: Nicole.boucheron@meduniwien.ac.at., Müller AC; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Májek P; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Claudel T; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Halilbasic E; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Baazim H; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Lercher A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Viczenczova C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Hainberger D; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Preglej T; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Sandner L; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Alteneder M; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Gülich AF; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Khan M; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Hamminger P; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Remetic J; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Ohradanova-Repic A; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Schatzlmaier P; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Donner C; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Fuchs CD; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Stojakovic T; Clinical Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Graz, Graz, Austria., Scharnagl H; Clinical Institute of Medical and Chemical Laboratory of Diagnostics, Medical University of Graz, Graz, Austria., Sakaguchi S; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Weichhart T; Institute of Medical Genetics, Center of Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria., Bergthaler A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Stockinger H; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Ellmeier W; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria., Trauner M; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address: michael.trauner@meduniwien.ac.at.
Source: Journal of hepatology [J Hepatol] 2021 Nov; Vol. 75 (5), pp. 1164-1176. Date of Electronic Publication: 2021 Jul 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: 24-Norursodeoxycholic acid reshapes immunometabolism in CD8<superscript>+</superscript> T cells and alleviates hepatic inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+C%22">Zhu C</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Boucheron+N%22">Boucheron N</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. Electronic address: Nicole.boucheron@meduniwien.ac.at.<br /><searchLink fieldCode="AU" term="%22Müller+AC%22">Müller AC</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Májek+P%22">Májek P</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Claudel+T%22">Claudel T</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Halilbasic+E%22">Halilbasic E</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Baazim+H%22">Baazim H</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Lercher+A%22">Lercher A</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Viczenczova+C%22">Viczenczova C</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hainberger+D%22">Hainberger D</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Preglej+T%22">Preglej T</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Sandner+L%22">Sandner L</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Alteneder+M%22">Alteneder M</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Gülich+AF%22">Gülich AF</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Khan+M%22">Khan M</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hamminger+P%22">Hamminger P</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Remetic+J%22">Remetic J</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ohradanova-Repic+A%22">Ohradanova-Repic A</searchLink>; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schatzlmaier+P%22">Schatzlmaier P</searchLink>; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Donner+C%22">Donner C</searchLink>; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Fuchs+CD%22">Fuchs CD</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Stojakovic+T%22">Stojakovic T</searchLink>; Clinical Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Scharnagl+H%22">Scharnagl H</searchLink>; Clinical Institute of Medical and Chemical Laboratory of Diagnostics, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Sakaguchi+S%22">Sakaguchi S</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Weichhart+T%22">Weichhart T</searchLink>; Institute of Medical Genetics, Center of Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Bergthaler+A%22">Bergthaler A</searchLink>; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Stockinger+H%22">Stockinger H</searchLink>; Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ellmeier+W%22">Ellmeier W</searchLink>; Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Trauner+M%22">Trauner M</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address: michael.trauner@meduniwien.ac.at.
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  Data: <searchLink fieldCode="JN" term="%228503886%22">Journal of hepatology</searchLink> [J Hepatol] 2021 Nov; Vol. 75 (5), pp. 1164-1176. <i>Date of Electronic Publication: </i>2021 Jul 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8503886 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1600-0641 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201688278%22">01688278 </searchLink><i>NLM ISO Abbreviation: </i>J Hepatol <i>Subsets: </i>MEDLINE
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