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1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/meta-substituted arenes.

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Title: 1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/meta-substituted arenes.
Authors: Zhao JX; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China., Chang YX; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., He C; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Burke BJ; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Collins MR; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121; michael.collins@pfizer.com pbaran@scripps.edu., Del Bel M; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Elleraas J; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Gallego GM; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Montgomery TP; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Mousseau JJ; Discovery Sciences, Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT 06340., Nair SK; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Perry MA; Discovery Sciences, Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT 06340., Spangler JE; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Vantourout JC; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Baran PS; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; michael.collins@pfizer.com pbaran@scripps.edu.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jul 13; Vol. 118 (28).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: 1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/meta-substituted arenes.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+JX%22">Zhao JX</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chang+YX%22">Chang YX</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22He+C%22">He C</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Burke+BJ%22">Burke BJ</searchLink>; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121.<br /><searchLink fieldCode="AU" term="%22Collins+MR%22">Collins MR</searchLink>; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121; michael.collins@pfizer.com pbaran@scripps.edu.<br /><searchLink fieldCode="AU" term="%22Del+Bel+M%22">Del Bel M</searchLink>; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121.<br /><searchLink fieldCode="AU" term="%22Elleraas+J%22">Elleraas J</searchLink>; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121.<br /><searchLink fieldCode="AU" term="%22Gallego+GM%22">Gallego GM</searchLink>; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121.<br /><searchLink fieldCode="AU" term="%22Montgomery+TP%22">Montgomery TP</searchLink>; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121.<br /><searchLink fieldCode="AU" term="%22Mousseau+JJ%22">Mousseau JJ</searchLink>; Discovery Sciences, Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT 06340.<br /><searchLink fieldCode="AU" term="%22Nair+SK%22">Nair SK</searchLink>; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121.<br /><searchLink fieldCode="AU" term="%22Perry+MA%22">Perry MA</searchLink>; Discovery Sciences, Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT 06340.<br /><searchLink fieldCode="AU" term="%22Spangler+JE%22">Spangler JE</searchLink>; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121.<br /><searchLink fieldCode="AU" term="%22Vantourout+JC%22">Vantourout JC</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Baran+PS%22">Baran PS</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; michael.collins@pfizer.com pbaran@scripps.edu.
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              Text: 2021 Jul 13
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